Crosstalk between cholesterol metabolism and psoriatic inflammation
L Luo, Y Guo, L Chen, J Zhu, C Li - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic autoinflammatory skin disease associated with multiple comorbidities,
with a prevalence ranging from 2 to 3% in the general population. Decades of preclinical …
with a prevalence ranging from 2 to 3% in the general population. Decades of preclinical …
Mevalonate kinase deficiency: current perspectives
LA Favier, GS Schulert - The application of clinical genetics, 2016 - Taylor & Francis
Mevalonate kinase deficiency (MKD) is a recessively inherited autoinflammatory disorder
with a spectrum of manifestations, including the well-defined clinical phenotypes of …
with a spectrum of manifestations, including the well-defined clinical phenotypes of …
Natural history of mevalonate kinase deficiency: a literature review
S Zhang - Pediatric Rheumatology, 2016 - Springer
Mevalonate kinase deficiency (MKD), a very rare autosomal recessive autoinflammatory
disease with multiple organ involvement, presents clinically as hyperimmunoglobulinemia D …
disease with multiple organ involvement, presents clinically as hyperimmunoglobulinemia D …
Hyper-IgD syndrome/mevalonate kinase deficiency: what is new?
CM Mulders-Manders, A Simon - Seminars in immunopathology, 2015 - Springer
Mevalonate kinase deficiency or hyper-IgD syndrome is a hereditary autoinflammatory
syndrome caused by mutations in the mevalonate kinase gene. In this review, we will …
syndrome caused by mutations in the mevalonate kinase gene. In this review, we will …
Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds
PM Tricarico, G Kleiner, E Valencic… - International journal of …, 2014 - mdpi.com
Deregulation of the mevalonate pathway is known to be involved in a number of diseases
that exhibit a systemic inflammatory phenotype and often neurological involvements, as …
that exhibit a systemic inflammatory phenotype and often neurological involvements, as …
Comparison of plant-based expression platforms for the heterologous production of geraniol
We compared the ability of different plant-based expression platforms to produce geraniol, a
key metabolite in the monoterpenoid branch of the terpenoid indole alkaloid biosynthesis …
key metabolite in the monoterpenoid branch of the terpenoid indole alkaloid biosynthesis …
Disposable bioreactors for cultivation of plant cell cultures
N Lehmann, I Dittler, M Lämsä, A Ritala… - Production of biomass …, 2014 - Springer
The trend for using disposable bioreactors in modern biotechnological processes has also
been adopted for plant cell cultivations. In fact, plant cell cultures are now being grown in …
been adopted for plant cell cultivations. In fact, plant cell cultures are now being grown in …
Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency
MA Munoz, OP Skinner… - The Journal of …, 2022 - Am Soc Clin Investig
Mevalonate kinase deficiency (MKD) is characterized by recurrent fevers and flares of
systemic inflammation, caused by biallelic loss-of-function mutations in MVK. The underlying …
systemic inflammation, caused by biallelic loss-of-function mutations in MVK. The underlying …
Cytokine signatures in hereditary fever syndromes (HFS)
JN Ibrahim, I Jeru, JC Lecron… - Cytokine & growth factor …, 2017 - Elsevier
Hereditary fever syndromes (HFS) include a group of disorders characterized by recurrent
self-limited episodes of fever accompanied by inflammatory manifestations occurring in the …
self-limited episodes of fever accompanied by inflammatory manifestations occurring in the …
Lack of prenylated proteins, autophagy impairment and apoptosis in SH-SY5Y neuronal cell model of mevalonate kinase deficiency
PM Tricarico, A Romeo, R Gratton, S Crovella… - Cellular Physiology and …, 2017 - karger.com
Abstract Background/Aims: Mevalonate Kinase Deficiency (MKD), is a hereditary disease
due to mutations in mevalonate kinase gene (MVK). MKD has heterogeneous clinical …
due to mutations in mevalonate kinase gene (MVK). MKD has heterogeneous clinical …