Medulloblastomics: the end of the beginning
The division of medulloblastoma into different subgroups by microarray expression profiling
has dramatically changed our perspective of this malignant childhood brain tumour. Now …
has dramatically changed our perspective of this malignant childhood brain tumour. Now …
Medulloblastoma—translating discoveries from the bench to the bedside
AJ Gajjar, GW Robinson - Nature reviews Clinical oncology, 2014 - nature.com
Medulloblastoma is a form of brain cancer that mainly arises during infancy and childhood.
Our understanding of this disease has transitioned rapidly; what was once thought of as a …
Our understanding of this disease has transitioned rapidly; what was once thought of as a …
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …
Clonal selection drives genetic divergence of metastatic medulloblastoma
Medulloblastoma, the most common malignant paediatric brain tumour, arises in the
cerebellum and disseminates through the cerebrospinal fluid in the leptomeningeal space to …
cerebellum and disseminates through the cerebrospinal fluid in the leptomeningeal space to …
Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis
Purpose Posterior fossa ependymoma comprises two distinct molecular variants termed
EPN_PFA and EPN_PFB that have a distinct biology and natural history. The therapeutic …
EPN_PFA and EPN_PFB that have a distinct biology and natural history. The therapeutic …
Behavioral and social outcomes in adolescent survivors of childhood cancer: a report from the childhood cancer survivor study
KAP Schultz, KK Ness, J Whitton, C Recklitis… - Journal of clinical …, 2007 - ascopubs.org
Purpose Adolescents, regardless of medical history, may face behavioral and social
challenges. Cancer and related treatments represent additional challenges for teens …
challenges. Cancer and related treatments represent additional challenges for teens …
Impact of craniospinal dose, boost volume, and neurologic complications on intellectual outcome in patients with medulloblastoma
Purpose To examine the impact of radiation (ie, craniospinal irradiation [CSR] dose and
boost volume) and complications (ie, hydrocephalus and other neurologic complications …
boost volume) and complications (ie, hydrocephalus and other neurologic complications …
A pilot study of an online cognitive rehabilitation program for executive function skills in children with cancer-related brain injury
SR Kesler, NJ Lacayo, B Jo - Brain injury, 2011 - Taylor & Francis
Primary objectives: Children with a history of cancer are at increased risk for cognitive
impairments, particularly in executive and memory domains. Traditional, in-person cognitive …
impairments, particularly in executive and memory domains. Traditional, in-person cognitive …
Cognitive changes in cancer survivors
Advances in cancer treatments have led to substantially improved survival for patients with
cancer. However, many patients experience changes in cognition as a side effect of both …
cancer. However, many patients experience changes in cognition as a side effect of both …
Neurocognitive and psychosocial outcomes in pediatric brain tumor survivors
PL Stavinoha, MA Askins, SK Powell, N Pillay Smiley… - Bioengineering, 2018 - mdpi.com
The late neurocognitive and psychosocial effects of treatment for pediatric brain tumor (PBT)
represent important areas of clinical focus and ongoing research. Neurocognitive sequelae …
represent important areas of clinical focus and ongoing research. Neurocognitive sequelae …