Urokinase-type plasminogen activator receptor (uPAR) expression is elevated during
inflammation and tissue remodelling and in many human cancers, in which it frequently …

Serpins are a superfamily of proteins, whose membership is based on the presence of a
single common core domain consisting of three β-sheets and 8-9 R-helices, and with a set of …

Oncogene-induced cellular senescence constitutes a strong anti-proliferative response,
which can be set in motion following either oncogene activation or loss of tumour suppressor …

The plasminogen system has been implicated in clot lysis, wound healing, tissue
regeneration, cancer and many other processes that affect health and disease. The …

The urokinase‐type plasminogen activator (u‐PA) system consists of the serine proteinases
plasmin and u‐PA; the serpin inhibitors α2‐anti‐plasmin, PAI‐1 and PAI‐2; and the u‐PA …

The LDL receptor–related protein (LRP) is larger than but structurally similar to other
members of the LDL receptor gene family, an ancient family of endocytic receptors (1–3) …

The ability to take up substances from the surrounding environment not only provides cells
with vital nutrients, but also enables the selective transport of substances from one …

The LDL receptor-related protein (originally called LRP, but now referred to as LRP1) is a
large endocytic receptor that is widely expressed in several tissues. LRP1 is a member of …

The recent cloning and sequencing of several insect vitellogenins (Vg), the major yolk
protein precursor of most oviparous animals, and the mosquito Vg receptor (VgR) has …

The low density lipoprotein receptor-related protein (LRP) Is a large multifunctional
clearance receptorthat has been implicated In the hepatlc uptake of chylomicron remnants …