Attempts to produce a vaccine to protect against Chlamydia trachomatis-induced trachoma
were initiated more than 100 years ago and continued for several decades. Using whole …

Most Chlamydia species carry a 7.5 kb plasmid encoding eight open reading frames
conventionally called plasmid glycoproteins 1–8 or pGP1–8. Although the plasmid is not …

The study of proteolysis lies at the heart of our understanding of biocatalysis, enzyme
evolution, and drug development. To understand the degree of natural variation in protease …

Chlamydia trachomatis, an obligate intracellular human pathogen, is a major cause of
sexually transmitted diseases. Infections often occur without symptoms, a feature that has …

Zymoseptoria tritici is the fungal pathogen responsible for Septoria tritici blotch on wheat.
Disease outcome in this pathosystem is partly determined by isolate-specific resistance …

Bacteria in the genus Chlamydia are major human pathogens that cause an intracellular
infection. A chlamydial protease, CPAF, has been proposed as an important virulence factor …

Chlamydia trachomatis serovars are obligate intracellular bacterial pathogens mainly
causing ocular and urogenital infections that affect millions of people worldwide and which …

Chlamydia trachomatis genital infection is a worldwide public health problem, and
considerable effort has been expended on developing an efficacious vaccine. The murine …

The MEROPS website (http://merops. sanger. ac. uk) includes information on peptidase
inhibitors as well as on peptidases and their substrates. Displays have been put in place to …

The failure of the inactivated Chlamydia-based vaccine trials in the 1960s has led
researchers studying Chlamydia to take cautious and rational approaches to develop safe …