[HTML][HTML] Streptomyces: The biofactory of secondary metabolites

K Alam, A Mazumder, S Sikdar, YM Zhao… - Frontiers in …, 2022 - frontiersin.org
Natural products derived from microorganisms serve as a vital resource of valuable
pharmaceuticals and therapeutic agents. Streptomyces is the most ubiquitous bacterial …

[HTML][HTML] Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

L Donald, A Pipite, R Subramani, J Owen… - Microbiology …, 2022 - mdpi.com
There is a real consensus that new antibiotics are urgently needed and are the best chance
for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers …

[HTML][HTML] Actinobacteria in natural products research: Progress and prospects

PA Jose, A Maharshi, B Jha - Microbiological research, 2021 - Elsevier
Actinobacteria are well-recognised biosynthetic factories that produce an extensive
spectrum of secondary metabolites. Recent genomic insights seem to impact the exploitation …

[HTML][HTML] Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic …

SP Gaudêncio, E Bayram, L Lukić Bilela, M Cueto… - Marine drugs, 2023 - mdpi.com
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

[HTML][HTML] Recent Advances in Silent Gene Cluster Activation in Streptomyces

Z Liu, Y Zhao, C Huang, Y Luo - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Natural products (NPs) are critical sources of drug molecules for decades. About two-thirds
of natural antibiotics are produced by Streptomyces. Streptomyces have a large number of …

[HTML][HTML] Bioactive metabolites from terrestrial and marine actinomycetes

C Ngamcharungchit, N Chaimusik, W Panbangred… - Molecules, 2023 - mdpi.com
Actinomycetes inhabit both terrestrial and marine ecosystems and are highly proficient in
producing a wide range of natural products with diverse biological functions, including …

Mining natural products for advanced biofuels and sustainable bioproducts

X Li, AE Gadar-Lopez, L Chen, S Jayachandran… - Current Opinion in …, 2023 - Elsevier
Highlights•Natural products offer a broad chemical catalog for bio-based product
development.•Genome mining tools for identifying BGCs.•Isoprenoid, nonribosomal peptide …

[HTML][HTML] Recent Progress of Reclassification of the Genus Streptomyces

H Komaki - Microorganisms, 2023 - mdpi.com
The genus Streptomyces is a representative group of actinomycetes and one of the largest
taxa in bacteria, including approximately 700 species with validly published names. Since …

StreptomeDB 3.0: an updated compendium of streptomycetes natural products

AFA Moumbock, M Gao, A Qaseem, J Li… - Nucleic acids …, 2021 - academic.oup.com
Antimicrobial resistance is an emerging global health threat necessitating the rapid
development of novel antimicrobials. Remarkably, the vast majority of currently available …

Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia

JWF Law, V Letchumanan… - … In Microbes & …, 2023 - journals.hh-publisher.com
Streptomyces learnhanii sp. nov. MUM 203J T was isolated from Malaysia mangrove soil.
This Gram-positive bacterium produces pale greenish-yellow aerial and greyish-yellow …