Peripheral nerve injury and axonotmesis: State of the art and recent advances

R Alvites, A Rita Caseiro, S Santos Pedrosa… - Cogent …, 2018 - Taylor & Francis
Peripheral nerve lesions are frequent occurrences in both human and animal patients,
leading to important physiological and labor complications that affect the quality of life of …

Platelet-rich plasma, a source of autologous growth factors and biomimetic scaffold for peripheral nerve regeneration

M Sánchez, E Anitua, D Delgado… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: In mammals, axons of injured peripheral nerves (PNI) can and do regenerate,
but often the functional recovery is incomplete or suboptimal. In recent years, in vivo tissue …

The multiple functions of melatonin in regenerative medicine

M Majidinia, RJ Reiter, SK Shakouri, I Mohebbi… - Ageing research …, 2018 - Elsevier
Melatonin research has been experiencing hyper growth in the last two decades; this relates
to its numerous physiological functions including anti-inflammation, oncostasis, circadian …

Effect of platelet‐rich plasma (PRP) concentration on proliferation, neurotrophic function and migration of Schwann cells in vitro

C Zheng, Q Zhu, X Liu, X Huang, C He… - Journal of tissue …, 2016 - Wiley Online Library
Platelet‐rich plasma (PRP) contains various growth factors and appears to have the
potential to promote peripheral nerve regeneration, but evidence is lacking regarding its …

Platelet-rich plasma, an adjuvant biological therapy to assist peripheral nerve repair

M Sánchez, A Garate, D Delgado… - Neural Regeneration …, 2017 - journals.lww.com
Therapies such as direct tension-free microsurgical repair or transplantation of a nerve
autograft, are nowadays used to treat traumatic peripheral nerve injuries (PNI), focused on …

Effect of platelet rich plasma and platelet rich fibrin on sciatic nerve regeneration in a rat model

M Lichtenfels, L Colomé, AD Sebben… - …, 2013 - Wiley Online Library
The aim of this study was to evaluate the effect of Platelet Rich Plasma (PRP) and Platelet
Rich Fibrin (PRF) on peripheral nerve repair. Thirty‐two Wistar rats were randomly divided …

Platelet-rich plasma promotes axon regeneration, wound healing, and pain reduction: fact or fiction

DP Kuffler - Molecular neurobiology, 2015 - Springer
Platelet-rich plasma (PRP) has been tested in vitro, in animal models, and clinically for its
efficacy in enhancing the rate of wound healing, reducing pain associated with injuries, and …

Healing effects of platelet-rich plasma on peripheral nerve injuries

F Bastami, P Vares, A Khojasteh - Journal of Craniofacial Surgery, 2017 - journals.lww.com
Regeneration of peripheral nerve injuries (PNIs) has been a major challenging issue in
regenerative medicine and tissue engineering. Inferior alveolar nerve and lingual nerve …

Current concepts and translational uses of platelet rich plasma biotechnology

I Andia, E Rubio-Azpeitia, JI Martin, M Abate - Biotechnology, 2015 - books.google.com
A two-decade long research has expedited knowledge about tissue repair mechanisms, and
the field of Regenerative Medicine is gaining ground stimulated by novel insights and the …

The influence of drugs on peripheral nerve regeneration

O Bota, L Fodor - Drug metabolism reviews, 2019 - Taylor & Francis
Currently, there are no established adjuvant drugs for the acceleration of peripheral nerve
regeneration. In this paper, we reviewed the literature from the last 10 years and described …