Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Z Chen, R Tian, Z She, J Cai, H Li - Free Radical Biology and Medicine, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Pathophysiological communication between hepatocytes and non-parenchymal cells in liver injury from NAFLD to liver fibrosis

S Kumar, Q Duan, R Wu, EN Harris, Q Su - Advanced drug delivery reviews, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease that encompasses a
spectrum of pathological conditions, ranging from simple steatosis (NAFL), nonalcoholic …

Triggering and resolution of inflammation in NASH

S Schuster, D Cabrera, M Arrese… - Nature reviews …, 2018 - nature.com
Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …

Chronic inflammation in non-alcoholic steatohepatitis: molecular mechanisms and therapeutic strategies

C Luci, M Bourinet, PS Leclère, R Anty… - Frontiers in …, 2020 - frontiersin.org
Non-Alcoholic Steatohepatitis (NASH) is the progressive form of Non-Alcoholic Fatty Liver
Disease (NAFLD), the main cause of chronic liver complications. The development of NASH …

[HTML][HTML] Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice

JH Zhou, JJ Cai, ZG She, HL Li - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver
disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults …

Toll-like receptors and metabolic (dysfunction)-associated fatty liver disease

S Khanmohammadi, MS Kuchay - Pharmacological research, 2022 - Elsevier
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) is characterized by the
accumulation of lipids in the liver (steatosis). In predisposed individuals, liver steatosis can …

[HTML][HTML] Invited review liver fibrosis in NAFLD/NASH: From pathophysiology towards diagnostic and therapeutic strategies

M Parola, M Pinzani - Molecular Aspects of Medicine, 2024 - Elsevier
Liver fibrosis, as an excess deposition of extracellular matrix (ECM) components, results
from chronic liver injury as well as persistent activation of inflammatory response and of …

Nonalcoholic fatty liver disease: an emerging driver of hypertension

YC Zhao, GJ Zhao, Z Chen, ZG She, J Cai, H Li - Hypertension, 2020 - Am Heart Assoc
Hypertension, a multifactorial disorder resulting from the interplay between genetic
predisposition and environmental risk factors, affects≈ 30% of adults. Emerging evidence …

Nonalcoholic fatty liver disease pandemic fuels the upsurge in cardiovascular diseases

J Cai, XJ Zhang, YX Ji, P Zhang, ZG She… - Circulation research, 2020 - Am Heart Assoc
Cardiovascular diseases (CVDs) remain a leading cause of death worldwide. Among the
major risk factors for CVD, obesity and diabetes mellitus have received considerable …

Advances in the diagnosis and treatment of non-alcoholic fatty liver disease

X Yin, X Guo, Z Liu, J Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease that
affects approximately one-quarter of the global adult population, posing a significant threat …