Scorpion venom: detriments and benefits

S Ahmadi, JM Knerr, L Argemi, KCF Bordon, MB Pucca… - Biomedicines, 2020 - mdpi.com
Scorpion venom may cause severe medical complications and untimely death if injected into
the human body. Neurotoxins are the main components of scorpion venom that are known to …

Venom peptides in cancer therapy: An updated review on cellular and molecular aspects

S Mirzaei, HS Fekri, F Hashemi, K Hushmandi… - Pharmacological …, 2021 - Elsevier
Based on the high incidence and mortality rates of cancer, its therapy remains one of the
most vital challenges in the field of medicine. Consequently, enhancing the efficacy of …

Aloe emodin relieves Ang II-induced endothelial junction dysfunction via promoting ubiquitination mediated NLRP3 inflammasome inactivation

Y Zhang, Z Song, S Huang, L Zhu, T Liu… - Journal of Leucocyte …, 2020 - academic.oup.com
Recent studies have revealed that aloe emodin (AE), a natural compound from the root and
rhizome of Rheum palmatum L., exhibits significant pharmacologic activities. However, the …

Scorpions, Science and Folklore in Durango City

E Gonzalez-Ponce, S Rodríguez-Rangel, R Martinez… - Diversity, 2023 - mdpi.com
Scorpions are incredible venomous animals found on almost every continent. According to
fossil data, these animals have been able to adapt to the different environments from the …

Scorpion Venom Peptides as Therapeutic Agents in Cardiovascular Diseases: A Systematic Review

FF Santos, M Silva, IM de Matos - International Journal of Peptide …, 2024 - Springer
Background Scorpions have evolved a highly efficient venom that serves both to capture
prey and for self-defense. As a result, peptides isolated from the venom of various scorpion …

The Potential Therapeutic Approach of Ursodeoxycholic Acid as a Potent Activator of ACE‐2 on Cerebral Disorders Induced by γ‐irradiation in Rats

SM Galal, SM El Kiki… - Cell Biochemistry and …, 2024 - Wiley Online Library
The present investigation assesses ursodeoxycholic acid's efficacy (UDCA) as an ACE2
activator against gamma irradiation through activating the renin‐angiotensin system's (RAS) …

The Nematocidal Effect of Leiurus quinquestratus Scorpion Venom on Toxocara canis in Mice Model

WM Salama, RA Elmahy - Journal of Experimental Zoology …, 2024 - Wiley Online Library
One neglected zoonotic illness is toxocariasis. There are not enough anthelmintic drugs in
the market to treat low‐effectiveness toxocariasis against migrating larvae. Therefore, it is …

Mitigative impact of bradykinin potentiating factor isolated from Androctonus amoreuxi scorpion venom and low doses of γ-irradiation on doxorubicin induced …

HF Hasan, SM Galal, RA Ellethy - Toxicology Mechanisms and …, 2022 - Taylor & Francis
In this study, the mitigative impact of bradykinin potentiating factor (BPF) and low doses of γ-
irradiation (LDR) were evaluated against doxorubicin (DOX) hepatotoxicity through Ang …

AOP report: Development of an adverse outcome pathway for deposition of energy leading to abnormal vascular remodeling

T Kozbenko, N Adam, VS Grybas… - Environmental and …, 2024 - Wiley Online Library
Cardiovascular diseases (CVDs) are complex, encompassing many types of heart
pathophysiologies and associated etiologies. Radiotherapy studies have shown that …

Scorpion bradykinin potentiating factor mitigates lung damage induced by γ-irradiation in rats: Insights on AngII/ACE/Ang (1–7) axis

HF Hasan, HK Mohmed, SM Galal - Toxicon, 2021 - Elsevier
The goal of this research is to study the mitigating impact of bradykinin potentiating factor
(BPF) found in scorpion Androctonus bicolor venom on irradiation-induced lung damage as …