Fertility control with oral medication
G Pincus, J Rock, CR Garcia, E Rice-Wray… - American journal of …, 1958 - Elsevier
As the outstanding findings resulting from this investigation, we may state the following: 1. 1.
Length of the Menstrual Cycle.—1.1. A. The ingestion of 10 mg. of norethynodrel …
Length of the Menstrual Cycle.—1.1. A. The ingestion of 10 mg. of norethynodrel …
Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation
MH Jeng, CJ Parker, VC Jordan - Cancer Research, 1992 - AACR
Most oral contraceptives (OC) contain a progestin in combination with an estrogen, and the
progestin component in OC includes one of the following 19-nortestosterone derivatives …
progestin component in OC includes one of the following 19-nortestosterone derivatives …
Control of Conception by Hormonal Steroids: There is no substantial evidence that the benefits of oral contraceptives are offset by adverse effects.
G Pincus - Science, 1966 - science.org
Experience with the use of progestinestrogen preparations as oral contraceptives indicates
that they inhibit fertility by preventing ovulation and that their action is clearly a physiological …
that they inhibit fertility by preventing ovulation and that their action is clearly a physiological …
Mechanism of action of hypothalamic hormones in the anterior pituitary gland and specific modulation of their activity by sex steroids and thyroid hormones
F LABRIE, J DROUIN, L FERLAND, L LAGACÉ… - Proceedings of the 1977 …, 1978 - Elsevier
Publisher Summary This chapter discusses the mechanism of action of hypothalamic
hormones in the anterior pituitary gland and specific modulation of their activity by sex …
hormones in the anterior pituitary gland and specific modulation of their activity by sex …
Effects of certain 19-nor steroids on reproductive processes in animals
In previous publications we have reported that progesterone and certain of its chemical
relatives are effective inhibitors of ovulation in rabbits, rats, and women (1-4). Among the …
relatives are effective inhibitors of ovulation in rabbits, rats, and women (1-4). Among the …
The secretion and metabolism of cortisol and aldosterone in normal and in steroid-treated women
D LAYNE, CJ Meyer, PS Vaishwanar… - The Journal of Clinical …, 1962 - academic.oup.com
The secretion rate and the pattern of metabolism of cortisol and of aldosterone were studied
in women receiving oral doses of Enovid, norethynodrel, ethynylestradiol 3-methyl ether …
in women receiving oral doses of Enovid, norethynodrel, ethynylestradiol 3-methyl ether …
Anti-ovulatory and other biological properties of megestrol acetate 17αacetoxy-6 methyl pregna 4: 6-diene-3: 20-dione (BDH 1298)
A David, K Edwards, KP Fellowes… - Reproduction, 1963 - rep.bioscientifica.com
17αAcetoxy-6 methyl pregna 4: 6-diene-3: 20-dione (BDH 1298), has been given the
approved name of Megestrol acetate. It appears to be the most potent anti-ovulatory …
approved name of Megestrol acetate. It appears to be the most potent anti-ovulatory …
Stereospecificity of the intracellular binding of norethisterone and its A-ring reduced metabolites
BA Chávez, F Vilchis, AE Pérez, GA García… - Journal of steroid …, 1985 - Elsevier
The interaction of norethisterone (NET) and four A-ring reduced metabolites of NET with
cytosol receptors for progesterone (PR), androgen (AR), and estrogen (ER) was …
cytosol receptors for progesterone (PR), androgen (AR), and estrogen (ER) was …
A comparative study of the metabolic fate of testosterone, 17α-methyl-testosterone, 19-nor-testos-terone, 7α-methyl-19-nor-testosterone and 17α-methyl-estr-5 (10) …
DF Dimick, M Heron, EE Baulieu, MF Jayle - Clinica Chimica Acta, 1961 - Elsevier
Single doses of 150 mg each of five different testosterone and nor-testosterone derivatives
were given to four normal male subjects and urinary excretions of 17-ketosteroids, 17 …
were given to four normal male subjects and urinary excretions of 17-ketosteroids, 17 …
Progestational activity of certain 19-nor steroids and progresterone derivatives
T MIYAKE, G PINCUS - Endocrinology, 1958 - academic.oup.com
Seven 19-norsteroids, 17α-ethinyl-19-nortestosterone (I), 17α-ethinyl-5 (10)-estraenolone
(II), 17α-ethyl-19-nortestosterone (III), 17α-methyl-19-nortestosterone (IV), 17α-propyl-l9 …
(II), 17α-ethyl-19-nortestosterone (III), 17α-methyl-19-nortestosterone (IV), 17α-propyl-l9 …