A systematic review of gene-by-intervention studies of alcohol and other substance use

ZE Neale, I Sally, C Kuo, DM Dick - Development and …, 2021 - cambridge.org
Alcohol and other substance use problems are common, and the efficacy of current
prevention and intervention programs is limited. Genetics may contribute to differential …

A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults

J Kim, A Park - The American journal on addictions, 2018 - Wiley Online Library
Background and Objectives Youth drinking is a pervasive public health concern with serious
negative developmental implications. Candidate gene and environment interaction studies …

Polygenic risk for aggression predicts adult substance use disorder diagnoses via substance use offending in emerging adulthood and is moderated by a family …

KK Elam, CJ Mun, J Kutzner, T Ha - Behavior genetics, 2021 - Springer
A substance use offense reflects an encounter with law enforcement and the court system in
response to breaking the law which may increase risk for substance use problems later in …

Longitudinal effects and environmental moderation of ALDH2 and ADH1B gene variants on substance use from age 14 to 40

GRB Saunders, M McGue, WG Iacono… - Development and …, 2022 - cambridge.org
Alcohol use and dependence are strongly affected by variation in aldehyde dehydrogenase
(ALDH2) and, to a lesser extent, alcohol dehydrogenase (ADH1B) genes. We use this …

Risk and Resilience Variants in the Retinoic Acid Metabolic and Developmental Pathways Associated with Risk of FASD Outcomes

L McKay, B Petrelli, M Pind, JN Reynolds, RF Wintle… - Biomolecules, 2024 - mdpi.com
Fetal Alcohol Spectrum Disorder (FASD) is a common neurodevelopmental disorder that
affects an estimated 2–5% of North Americans. FASD is induced by prenatal alcohol …

A case study in developmental discontinuity: PROSPER Interventions and adolescent substance use trajectories shape young adult substance use and mental health …

GM Fosco, S Fang, L Chen… - Journal of research …, 2024 - Wiley Online Library
Abstract The loss of John Schulenberg reverberates across the developmental and
prevention sciences. In honor of his many contributions, this paper applies his ideas of …

Effects of fathers on adolescent daughters' frequency of substance use and risky sexual behavior

DJ DelPriore, SA Brener, SE Hill… - Journal of Research on …, 2021 - Wiley Online Library
This research:(1) implements a genetically informed design to examine the effects of fathers'
presence–absence and quality of behavior during childhood/adolescence on daughters' …

Genetic moderation of the effects of family‐focused interventions (GxI interaction): A systematic review.

L Li, J Zhang, JH Rudi… - Journal of Family Theory & …, 2022 - search.ebscohost.com
Abstract Gene by Intervention (GxI) interaction studies examine how a person's genotype
may moderate (ie, increase or decrease benefit from) an intervention's impact, typically in …

Longitudinal links between adolescent and peer conduct problems and moderation by a sensitivity genetic index

GL Schlomer, HH Cleveland… - Journal of Research …, 2021 - Wiley Online Library
The most extensively studied influence on adolescent conduct problem behaviors is peers,
and the literature points to genetics as one source of individual differences in peer influence …

Developmental Change in Adolescent Delinquency: Modeling Time-Varying Effects of a Preventative Intervention and GABRA2 Halpotype Linked to Alcohol Use

GL Schlomer, HH Cleveland, AR Deutsch… - Journal of youth and …, 2019 - Springer
Better integrating human developmental factors in genomic research is part of a set of next
steps for testing gene-by-environment interaction hypotheses. This study adds to this work …