A systematic review of gene-by-intervention studies of alcohol and other substance use
Alcohol and other substance use problems are common, and the efficacy of current
prevention and intervention programs is limited. Genetics may contribute to differential …
prevention and intervention programs is limited. Genetics may contribute to differential …
A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults
J Kim, A Park - The American journal on addictions, 2018 - Wiley Online Library
Background and Objectives Youth drinking is a pervasive public health concern with serious
negative developmental implications. Candidate gene and environment interaction studies …
negative developmental implications. Candidate gene and environment interaction studies …
Polygenic risk for aggression predicts adult substance use disorder diagnoses via substance use offending in emerging adulthood and is moderated by a family …
A substance use offense reflects an encounter with law enforcement and the court system in
response to breaking the law which may increase risk for substance use problems later in …
response to breaking the law which may increase risk for substance use problems later in …
Longitudinal effects and environmental moderation of ALDH2 and ADH1B gene variants on substance use from age 14 to 40
Alcohol use and dependence are strongly affected by variation in aldehyde dehydrogenase
(ALDH2) and, to a lesser extent, alcohol dehydrogenase (ADH1B) genes. We use this …
(ALDH2) and, to a lesser extent, alcohol dehydrogenase (ADH1B) genes. We use this …
Risk and Resilience Variants in the Retinoic Acid Metabolic and Developmental Pathways Associated with Risk of FASD Outcomes
L McKay, B Petrelli, M Pind, JN Reynolds, RF Wintle… - Biomolecules, 2024 - mdpi.com
Fetal Alcohol Spectrum Disorder (FASD) is a common neurodevelopmental disorder that
affects an estimated 2–5% of North Americans. FASD is induced by prenatal alcohol …
affects an estimated 2–5% of North Americans. FASD is induced by prenatal alcohol …
A case study in developmental discontinuity: PROSPER Interventions and adolescent substance use trajectories shape young adult substance use and mental health …
Abstract The loss of John Schulenberg reverberates across the developmental and
prevention sciences. In honor of his many contributions, this paper applies his ideas of …
prevention sciences. In honor of his many contributions, this paper applies his ideas of …
Effects of fathers on adolescent daughters' frequency of substance use and risky sexual behavior
This research:(1) implements a genetically informed design to examine the effects of fathers'
presence–absence and quality of behavior during childhood/adolescence on daughters' …
presence–absence and quality of behavior during childhood/adolescence on daughters' …
Genetic moderation of the effects of family‐focused interventions (GxI interaction): A systematic review.
Abstract Gene by Intervention (GxI) interaction studies examine how a person's genotype
may moderate (ie, increase or decrease benefit from) an intervention's impact, typically in …
may moderate (ie, increase or decrease benefit from) an intervention's impact, typically in …
Longitudinal links between adolescent and peer conduct problems and moderation by a sensitivity genetic index
GL Schlomer, HH Cleveland… - Journal of Research …, 2021 - Wiley Online Library
The most extensively studied influence on adolescent conduct problem behaviors is peers,
and the literature points to genetics as one source of individual differences in peer influence …
and the literature points to genetics as one source of individual differences in peer influence …
Developmental Change in Adolescent Delinquency: Modeling Time-Varying Effects of a Preventative Intervention and GABRA2 Halpotype Linked to Alcohol Use
Better integrating human developmental factors in genomic research is part of a set of next
steps for testing gene-by-environment interaction hypotheses. This study adds to this work …
steps for testing gene-by-environment interaction hypotheses. This study adds to this work …