Mammalian cells integrate different types of stimuli that govern their fate. These stimuli
encompass biochemical as well as biomechanical cues (shear, tensile, and compressive …

Apoptosis, the most extensively studied form of programmed cell death, is essential for
organismal homeostasis. Apoptotic cell death has widely been reported as a tumor …

Mechanical forces are critical regulators of cell shape changes and developmental
morphogenetic processes. Forces generated along the epithelium apico-basal cell axis …

The transition from monolayers to multilayered structures in bacterial colonies is a
fundamental step in biofilm development. Observed across different morphotypes and …

Programmed cell death, notably apoptosis, is an essential guardian of tissue homeostasis
and an active contributor of organ shaping. While the regulation of apoptosis has been …

Apoptosis is a mechanism of eliminating damaged or unnecessary cells during development
and tissue homeostasis. During apoptosis within a tissue, the adhesions between dying and …

Far from being passive, apoptotic cells influence their environment. For example, they
promote tissue folding, myoblast fusion and modulate tumor growth. Understanding the role …

Accurately counting and localising cellular events from movies is an important bottleneck of
high-content tissue/embryo live imaging. Here, we propose a new methodology based on …

The expulsion of dying epithelial cells requires well-orchestrated remodelling steps to
maintain tissue sealing. This process, named cell extrusion, has been mostly analysed …

Epithelia can eliminate apoptotic cells by apical extrusion. This is a complex morphogenetic
event where expulsion of the apoptotic cell is accompanied by rearrangement of its …