[HTML][HTML] Exosomes–Spectacular role in reproduction

A Kowalczyk, M Wrzecińska… - Biomedicine & …, 2022 - Elsevier
Exosomes are nano-sized structures that are found in semen, epididymal–fluid,
endometrium, as well as in follicular fluid. They are responsible for transporting bioactive …

Mammalian cumulus-oocyte complex communication: a dialog through long and short distance messaging

M Marchais, I Gilbert, A Bastien, A Macaulay… - Journal of Assisted …, 2022 - Springer
Communications are crucial to ovarian follicle development and to ovulation, and while both
folliculogenesis and oogenesis are distinct processes, they share highly interdependent …

Reproductive physiology of the heat-stressed dairy cow: implications for fertility and assisted reproduction

PJ Hansen - Animal Reproduction, 2019 - SciELO Brasil
Heat stress causes a large decline in pregnancy success per insemination during warm
times of the year. Improvements in fertility are possible by exploiting knowledge about how …

Exosomal miR-143-3p derived from follicular fluid promotes granulosa cell apoptosis by targeting BMPR1A in polycystic ovary syndrome

Y Zhao, S Pan, Y Li, X Wu - Scientific reports, 2022 - nature.com
Polycystic ovary syndrome (PCOS) is an endocrine disorder that occurs in women of
reproductive age. Anovulation caused by abnormal follicular development is still the main …

Follicular fluid-derived exosomal MicroRNA-18b-5p regulates PTEN-mediated PI3K/Akt/mTOR signaling pathway to inhibit polycystic ovary syndrome development

Z Zhou, Z Tu, J Zhang, C Tan, X Shen, B Wan, Y Li… - Molecular …, 2022 - Springer
Small RNA sequences in follicular fluid (FF)-derived exosomes (extracellular vesicles
contain proteins, DNA, and RNA) vitally function in the development of polycystic ovary …

PCOS follicular fluid derived exosomal miR-424-5p induces granulosa cells senescence by targeting CDCA4 expression

D Yuan, J Luo, Y Sun, L Hao, J Zheng, Z Yang - Cellular Signalling, 2021 - Elsevier
Polycystic ovary syndrome (PCOS) is a heterogeneous reproductive disease, characterized
by increased ovarian androgen biosynthesis, chronic anovulation and polycystic ovaries …

Prospects for gene introgression or gene editing as a strategy for reduction of the impact of heat stress on production and reproduction in cattle

PJ Hansen - Theriogenology, 2020 - Elsevier
In cattle, genetic variation exists in regulation of body temperature and stabilization of
cellular function during heat stress. There are opportunities to reduce the impact of heat …

[HTML][HTML] Exosomes: New regulators of reproductive development

C Chen, Z Zhang, X Gu, X Sheng, L Xiao, X Wang - Materials Today Bio, 2023 - Elsevier
Exosomes are a subtype of extracellular vesicles (EVs) with a size range between 30 and
150​ nm, which can be released by the majority of cell types and circulate in body fluid …

The role of microRNAs in mammalian fertility: From gametogenesis to embryo implantation

D Salilew-Wondim, S Gebremedhn, M Hoelker… - International journal of …, 2020 - mdpi.com
The genetic codes inscribed during two key developmental processes, namely
gametogenesis and embryogenesis, are believed to determine subsequent development …

Protein cargo of extracellular vesicles from bovine follicular fluid and analysis of their origin from different ovarian cells

S Uzbekova, C Almiñana, V Labas… - Frontiers in veterinary …, 2020 - frontiersin.org
Follicular fluid (FF) fills the interior portion of the ovarian antral follicle and provides a
suitable microenvironment for the growth of the enclosed oocyte through molecular factors …