Compromised carbohydrate metabolism leading to hyperglycemia is the primary metabolic
disorder of non-insulin-dependent diabetes mellitus. Reformed digestion and altered …

In this paper, the biosynthesis process of phenolic compounds in plants is summarized,
which include the shikimate, pentose phosphate and phenylpropanoid pathways. Plant …

Significant evidence from epidemiological investigations showed that dietary polyphenols
might manage and prevent type 2 diabetes (T2D). This review summarizes human studies …

Intracellular glucose and lipid metabolic homeostasis is vital for maintaining basic life
activities of a cell or an organism. Glucose and lipid metabolic disorders are closely related …

Optimized nutrition through supplementation of diet with plant derived phytochemicals has
attracted significant attention to prevent the onset of many chronic diseases including …

In recent years, there is growing evidence that plant-foods polyphenols, due to their
biological properties, may be unique nutraceuticals and supplementary treatments for …

Objectives and design Chlorogenic acid, which belongs to the polyphenols, is an anti-
oxidant and anti-obesity agent. In this study, we investigated the role of chlorogenic acid in …

Polyphenols, including flavonoids, phenolic acids, proanthocyanidins and resveratrol, are a
large and heterogeneous group of phytochemicals in plant-based foods, such as tea, coffee …

Chlorogenic acid (CGA) has been shown to stimulate glucose uptake in skeletal muscle
through the activation of AMPK. However, its effect on other metabolic pathways and …

Diabetes mellitus (DM) has become a major public health threat across the globe. Current
antidiabetic therapies are based on synthetic drugs that very often have side effects. It has …