Biomedical applications of tannic acid
Tannic Acid (TA) is a naturally occurring antioxidant polyphenol that has gained popularity
over the past decade in the field of biomedical research for its unique biochemical …
over the past decade in the field of biomedical research for its unique biochemical …
Targeting the ubiquitin-proteasome pathway to overcome anti-cancer drug resistance
Drug resistance is a major obstacle in the field of pre-clinical and clinical therapeutics. The
development of novel technologies and targeted therapies have yielded new modalities to …
development of novel technologies and targeted therapies have yielded new modalities to …
ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP
JH Maltbaek, S Cambier, JM Snyder, DB Stetson - Immunity, 2022 - cell.com
The DNA sensor cyclic GMP-AMP synthase (cGAS) is important for antiviral and anti-tumor
immunity. cGAS generates cyclic GMP-AMP (cGAMP), a diffusible cyclic dinucleotide that …
immunity. cGAS generates cyclic GMP-AMP (cGAMP), a diffusible cyclic dinucleotide that …
ABC transporter-mediated multidrug-resistant cancer
ATP-binding cassette (ABC) transporters are involved in active pumping of many diverse
substrates through the cellular membrane. The transport mediated by these proteins …
substrates through the cellular membrane. The transport mediated by these proteins …
Deep learning accurately predicts estrogen receptor status in breast cancer metabolomics data
FM Alakwaa, K Chaudhary… - Journal of proteome …, 2018 - ACS Publications
Metabolomics holds the promise as a new technology to diagnose highly heterogeneous
diseases. Conventionally, metabolomics data analysis for diagnosis is done using various …
diseases. Conventionally, metabolomics data analysis for diagnosis is done using various …
Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies
FH Tan, TL Putoczki, SS Stylli… - OncoTargets and therapy, 2019 - Taylor & Francis
Human malignancies are often the result of overexpressed and constitutively active receptor
and non-receptor tyrosine kinases, which ultimately lead to the mediation of key tumor …
and non-receptor tyrosine kinases, which ultimately lead to the mediation of key tumor …
Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor
Q Yin, J Shen, Z Zhang, H Yu, Y Li - Advanced drug delivery reviews, 2013 - Elsevier
Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …
The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …
Cancer chemoprevention through dietary flavonoids: what's limiting?
Flavonoids are polyphenols that are found in numerous edible plant species. Data obtained
from preclinical and clinical studies suggest that specific flavonoids are chemo-preventive …
from preclinical and clinical studies suggest that specific flavonoids are chemo-preventive …
ABC transporters in breast cancer: their roles in multidrug resistance and beyond
ATP-binding cassette (ABC) transporters are membrane-spanning proteins involved in
cholesterol homeostasis, transport of various molecules in and out of cells and organelles …
cholesterol homeostasis, transport of various molecules in and out of cells and organelles …