Biomedical applications of tannic acid

A Baldwin, BW Booth - Journal of Biomaterials Applications, 2022 - journals.sagepub.com
Tannic Acid (TA) is a naturally occurring antioxidant polyphenol that has gained popularity
over the past decade in the field of biomedical research for its unique biochemical …

Targeting the ubiquitin-proteasome pathway to overcome anti-cancer drug resistance

S Narayanan, CY Cai, YG Assaraf, HQ Guo… - Drug Resistance …, 2020 - Elsevier
Drug resistance is a major obstacle in the field of pre-clinical and clinical therapeutics. The
development of novel technologies and targeted therapies have yielded new modalities to …

ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP

JH Maltbaek, S Cambier, JM Snyder, DB Stetson - Immunity, 2022 - cell.com
The DNA sensor cyclic GMP-AMP synthase (cGAS) is important for antiviral and anti-tumor
immunity. cGAS generates cyclic GMP-AMP (cGAMP), a diffusible cyclic dinucleotide that …

ABC transporter-mediated multidrug-resistant cancer

H Amawi, HM Sim, AK Tiwari, SV Ambudkar… - Drug transporters in …, 2019 - Springer
ATP-binding cassette (ABC) transporters are involved in active pumping of many diverse
substrates through the cellular membrane. The transport mediated by these proteins …

Deep learning accurately predicts estrogen receptor status in breast cancer metabolomics data

FM Alakwaa, K Chaudhary… - Journal of proteome …, 2018 - ACS Publications
Metabolomics holds the promise as a new technology to diagnose highly heterogeneous
diseases. Conventionally, metabolomics data analysis for diagnosis is done using various …

Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies

FH Tan, TL Putoczki, SS Stylli… - OncoTargets and therapy, 2019 - Taylor & Francis
Human malignancies are often the result of overexpressed and constitutively active receptor
and non-receptor tyrosine kinases, which ultimately lead to the mediation of key tumor …

Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor

Q Yin, J Shen, Z Zhang, H Yu, Y Li - Advanced drug delivery reviews, 2013 - Elsevier
Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …

The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics

BHJ Gowda, MG Ahmed, SA Alshehri, S Wahab… - Environmental …, 2023 - Elsevier
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …

Cancer chemoprevention through dietary flavonoids: what's limiting?

H Amawi, CR Ashby, AK Tiwari - Chinese journal of cancer, 2017 - Springer
Flavonoids are polyphenols that are found in numerous edible plant species. Data obtained
from preclinical and clinical studies suggest that specific flavonoids are chemo-preventive …

ABC transporters in breast cancer: their roles in multidrug resistance and beyond

A Modi, D Roy, S Sharma, JR Vishnoi… - Journal of Drug …, 2022 - Taylor & Francis
ATP-binding cassette (ABC) transporters are membrane-spanning proteins involved in
cholesterol homeostasis, transport of various molecules in and out of cells and organelles …