The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

Recombination is a prominent feature of meiosis in which it plays an important role in
increasing genetic diversity during inheritance. Additionally, in most organisms …

In a recent publication, Ma et al. 1 reported the correction of a heterozygous paternally
inherited MYBPC3 mutation in human zygotes using CRISPR–Cas9 genome editing. We …

In this review, we discuss the repair of DNA double-strand breaks (DSBs) using a
homologous DNA sequence (ie, homologous recombination [HR]), focusing mainly on yeast …

During meiosis, a programmed induction of DNA double-strand breaks (DSBs) leads to the
exchange of genetic material between homologous chromosomes. These exchanges …

Meiotic recombination involves the formation and repair of programmed DNA double-strand
breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent …

Heritability and genome stability are shaped by meiotic recombination, which is initiated via
hundreds of DNA double-strand breaks (DSBs). The distribution of DSBs throughout the …

Meiotic recombination commences with hundreds of programmed DNA breaks; however, the
degree to which they are accurately repaired remains poorly understood. We report that …

The synaptonemal complex (SC) is a meiosis-specific scaffold that links homologous
chromosomes from end to end during meiotic prophase and is required for the formation of …

Recombination in meiosis is a fascinating case study for the coordination of chromosomal
duplication, repair, and segregation with each other and with progression through a cell …