Gut–organ axis: a microbial outreach and networking

S Ahlawat, Asha, KK Sharma - Letters in applied microbiology, 2021 - academic.oup.com
Human gut microbiota (GM) includes a complex and dynamic population of microorganisms
that are crucial for well‐being and survival of the organism. It has been reported as diverse …

Ageing and inflammation in patients with HIV infection

M Nasi, S De Biasi, L Gibellini… - Clinical & …, 2017 - academic.oup.com
Nowadays, HIV+ patients have an expected lifespan that is only slightly shorter than healthy
individuals. For this reason, along with the fact that infection can be acquired at a relatively …

Immunology of osteoporosis: a mini-review

P Pietschmann, D Mechtcheriakova… - Gerontology, 2016 - karger.com
Osteoporosis is a major cause of fractures and associated morbidity in the aged population.
The pathogenesis of osteoporosis is multifactorial; whereas traditional pathophysiological …

Physiological and pathophysiological bone turnover—role of the immune system

MN Weitzmann, I Ofotokun - Nature Reviews Endocrinology, 2016 - nature.com
Osteoporosis develops when the rate of osteoclastic bone breakdown (resorption) exceeds
that of osteoblastic bone formation, which leads to loss of BMD and deterioration of bone …

[PDF][PDF] Osteoimmunology: The Nexus between bone and immune system

HY Dar, Z Azam, R Anupam, RK Mondal… - Front Biosci …, 2018 - article.imrpress.com
Osteoimmunology is an interdisciplinary research field which combines the existing fields of
osteology (bone biology) and immunology under one umbrella. The observation that …

The role of inflammatory cytokines, the RANKL/OPG axis, and the immunoskeletal interface in physiological bone turnover and osteoporosis

MN Weitzmann - Scientifica, 2013 - Wiley Online Library
Although it has long been recognized that inflammation, a consequence of immune‐driven
processes, significantly impacts bone turnover, the degree of centralization of skeletal and …

T and B cells participate in bone repair by infiltrating the fracture callus in a two-wave fashion

I Könnecke, A Serra, T El Khassawna, C Schlundt… - Bone, 2014 - Elsevier
Fracture healing is a regenerative process in which bone is restored without scar tissue
formation. The healing cascade initiates with a cycle of inflammation, cell migration …

The road to elimination: current state of schistosomiasis research and progress towards the end game

P Ogongo, RK Nyakundi, GK Chege… - Frontiers in …, 2022 - frontiersin.org
The new WHO Roadmap for Neglected Tropical Diseases targets the global elimination of
schistosomiasis as a public health problem. To date, control strategies have focused on …

Bioactive silica-based nanoparticles stimulate bone-forming osteoblasts, suppress bone-resorbing osteoclasts, and enhance bone mineral density in vivo

GR Beck Jr, SW Ha, CE Camalier, M Yamaguchi… - … , Biology and Medicine, 2012 - Elsevier
Bone is a dynamic tissue that undergoes renewal throughout life in a process whereby
osteoclasts resorb worn bone and osteoblasts synthesize new bone. Imbalances in bone …

The interplay between the bone and the immune system

G Mori, PD′ Amelio, R Faccio… - Journal of Immunology …, 2013 - Wiley Online Library
In the last two decades, numerous scientists have highlighted the interactions between bone
and immune cells as well as their overlapping regulatory mechanisms. For example …