Small-molecule fluorophores and fluorescent probes for bioimaging

T Terai, T Nagano - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
Fluorescent compounds based on synthetic small molecules are powerful tools to visualize
biological events in living cells and organisms. Ever since the discovery of organic …

Fluorescence lifetime techniques in medical applications

L Marcu - Annals of biomedical engineering, 2012 - Springer
This article presents an overview of time-resolved (lifetime) fluorescence techniques used in
biomedical diagnostics. In particular, we review the development of time-resolved …

Near‐infrared Raman spectroscopy for optical diagnosis of lung cancer

Z Huang, A McWilliams, H Lui… - … journal of cancer, 2003 - Wiley Online Library
Raman spectroscopy is a vibrational spectroscopic technique that can be used to optically
probe the molecular changes associated with diseased tissues. The objective of our study …

Cell-phone-based platform for biomedical device development and education applications

ZJ Smith, K Chu, AR Espenson, M Rahimzadeh… - PloS one, 2011 - journals.plos.org
In this paper we report the development of two attachments to a commercial cell phone that
transform the phone's integrated lens and image sensor into a 350× microscope and visible …

Colorectal cancer detection by gold nanoparticle based surface-enhanced Raman spectroscopy of blood serum and statistical analysis

D Lin, S Feng, J Pan, Y Chen, J Lin, G Chen, S Xie… - Optics express, 2011 - opg.optica.org
The capabilities of using gold nanoparticle based surface-enhanced Raman spectroscopy
(SERS) to obtain blood serum biochemical information for non-invasive colorectal cancer …

Micro‐Raman spectroscopy used to identify and grade human skin pilomatrixoma

WT Cheng, MT Liu, HN Liu… - Microscopy research and …, 2005 - Wiley Online Library
Raman microspectroscopy was applied to analyze the changes in structural conformation
and chemical composition of the mass of human skin pilomatrixoma (PMX). The normal skin …

NAD(P)H and Collagen as in Vivo Quantitative Fluorescent Biomarkers of Epithelial Precancerous Changes

I Georgakoudi, BC Jacobson, MG Muller, EE Sheets… - Cancer research, 2002 - AACR
During the development of neoplasia, epithelial tissues undergo biochemical and structural
changes that can manifest in tissue fluorescence. There have been several reports on …

Skin cancer detection using non-invasive techniques

V Narayanamurthy, P Padmapriya, A Noorasafrin… - RSC …, 2018 - pubs.rsc.org
Skin cancer is the most common form of cancer and is globally rising. Historically, the
diagnosis of skin cancers has depended on various conventional techniques which are of …

Lighting up tumors with receptor-specific optical molecular probes

S Achilefu - Technology in cancer research & treatment, 2004 - journals.sagepub.com
Accurate and rapid detection of tumors is of great importance for interrogating the molecular
basis of cancer pathogenesis, preventing the onset of complications, and implementing a …

Diagnosis of nonmelanoma skin cancer/keratinocyte carcinoma: a review of diagnostic accuracy of nonmelanoma skin cancer diagnostic tests and technologies

M Mogensen, GBE Jemec - Dermatologic Surgery, 2007 - journals.lww.com
BACKGROUND Nonmelanoma skin cancer (NMSC) is the most prevalent cancer in the light-
skinned population. Noninvasive treatment is increasingly used for NMSC patients with …