Next-generation TB vaccines: progress, challenges, and prospects
L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …
infectious disease and a leading cause of mortality worldwide. Currently, the only available …
In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …
Improving protection to prevent bacterial infections: preliminary applications of reverse vaccinology against the main cystic fibrosis pathogens
M Cocorullo, LR Chiarelli, G Stelitano - Vaccines, 2023 - mdpi.com
Reverse vaccinology is a powerful tool that was recently used to develop vaccines starting
from a pathogen genome. Some bacterial infections have the necessity to be prevented then …
from a pathogen genome. Some bacterial infections have the necessity to be prevented then …
Computational design of a multi-epitope vaccine candidate against Langya henipavirus using surface proteins
Abstract In July 2022, Langya henipavirus (LayV) was identified in febrile patients in China.
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
[HTML][HTML] Genome-level therapeutic targets identification and chimeric Vaccine designing against the Blastomyces dermatitidis
S Mursaleen, A Sarfraz, M Shehroz, A Zaman… - Heliyon, 2024 - cell.com
Blastomyces dermatitidis is a thermally dimorphic fungus that can cause serious and
sometimes fatal infections, including blastomycosis. After spore inhalation, a pulmonary …
sometimes fatal infections, including blastomycosis. After spore inhalation, a pulmonary …
[HTML][HTML] In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis
BT Andongma, Y Huang, F Chen, Q Tang… - Computational and …, 2023 - Elsevier
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
Designing a novel chimeric multi-epitope vaccine subunit against Staphylococcus argenteus through artificial intelligence approach integrating pan-genome analysis …
Staphylococcus argenteus is a newly identified pathogen that causes respiratory tract
infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is …
infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is …
Immunoinformatics design of multi-epitope vaccine using OmpA, OmpD and enterotoxin against non-typhoidal salmonellosis
B Beikzadeh - BMC bioinformatics, 2023 - Springer
Abstract Background Non-typhoidal Salmonella (NTS) is one of the important bacteria that
cause foodborne diseases and invasive infections in children and elderly people. Since NTS …
cause foodborne diseases and invasive infections in children and elderly people. Since NTS …
Immunoinformatic-guided designing of multi-epitope vaccine construct against Brucella Suis 1300
K Jalal, K Khan, R Uddin - Immunologic Research, 2023 - Springer
Brucella suis mediates the transmission of brucellosis in humans and animals and a
significant facultative zoonotic pathogen found in livestock. It has the capacity to survive and …
significant facultative zoonotic pathogen found in livestock. It has the capacity to survive and …
Multi-epitopes vaccine design for surface glycoprotein against SARS-CoV-2 using immunoinformatic approach
Background The recent COVID vaccinations have successfully reduced death and severity
but did not stop the transmission of viruses by the emerging SARS-CoV-2 strain. There is a …
but did not stop the transmission of viruses by the emerging SARS-CoV-2 strain. There is a …