Next-generation TB vaccines: progress, challenges, and prospects

L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

S Sanami, S Nazarian, S Ahmad, E Raeisi… - Plos one, 2023 - journals.plos.org
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …

Improving protection to prevent bacterial infections: preliminary applications of reverse vaccinology against the main cystic fibrosis pathogens

M Cocorullo, LR Chiarelli, G Stelitano - Vaccines, 2023 - mdpi.com
Reverse vaccinology is a powerful tool that was recently used to develop vaccines starting
from a pathogen genome. Some bacterial infections have the necessity to be prevented then …

Computational design of a multi-epitope vaccine candidate against Langya henipavirus using surface proteins

S Ahmad, S Nazarian, A Alizadeh… - Journal of …, 2024 - Taylor & Francis
Abstract In July 2022, Langya henipavirus (LayV) was identified in febrile patients in China.
There is currently no approved vaccine against this virus. Therefore, this research aimed to …

[HTML][HTML] Genome-level therapeutic targets identification and chimeric Vaccine designing against the Blastomyces dermatitidis

S Mursaleen, A Sarfraz, M Shehroz, A Zaman… - Heliyon, 2024 - cell.com
Blastomyces dermatitidis is a thermally dimorphic fungus that can cause serious and
sometimes fatal infections, including blastomycosis. After spore inhalation, a pulmonary …

[HTML][HTML] In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis

BT Andongma, Y Huang, F Chen, Q Tang… - Computational and …, 2023 - Elsevier
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …

Designing a novel chimeric multi-epitope vaccine subunit against Staphylococcus argenteus through artificial intelligence approach integrating pan-genome analysis …

M Naveed, S Mahmood, T Aziz, A Azeem… - Journal of …, 2024 - Taylor & Francis
Staphylococcus argenteus is a newly identified pathogen that causes respiratory tract
infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is …

Immunoinformatics design of multi-epitope vaccine using OmpA, OmpD and enterotoxin against non-typhoidal salmonellosis

B Beikzadeh - BMC bioinformatics, 2023 - Springer
Abstract Background Non-typhoidal Salmonella (NTS) is one of the important bacteria that
cause foodborne diseases and invasive infections in children and elderly people. Since NTS …

Immunoinformatic-guided designing of multi-epitope vaccine construct against Brucella Suis 1300

K Jalal, K Khan, R Uddin - Immunologic Research, 2023 - Springer
Brucella suis mediates the transmission of brucellosis in humans and animals and a
significant facultative zoonotic pathogen found in livestock. It has the capacity to survive and …

Multi-epitopes vaccine design for surface glycoprotein against SARS-CoV-2 using immunoinformatic approach

SF Arshad, R Rehana, MA Saleem, M Usman… - Heliyon, 2024 - cell.com
Background The recent COVID vaccinations have successfully reduced death and severity
but did not stop the transmission of viruses by the emerging SARS-CoV-2 strain. There is a …