Gut microbiota and cardiovascular disease: opportunities and challenges

N Kazemian, M Mahmoudi, F Halperin, JC Wu… - Microbiome, 2020 - Springer
Coronary artery disease (CAD) is the most common health problem worldwide and remains
the leading cause of morbidity and mortality. Over the past decade, it has become clear that …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Nanoparticle-mediated drug delivery for the treatment of cardiovascular diseases

R Pala, VT Anju, M Dyavaiah, S Busi… - International journal of …, 2020 - Taylor & Francis
Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and
mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are …

Silica–gold nanoparticles for atheroprotective management of plaques: results of the NANOM-FIM trial

AN Kharlamov, AE Tyurnina, VS Veselova, OP Kovtun… - Nanoscale, 2015 - pubs.rsc.org
Background: Atheroregression becomes an attractive target for cardiovascular treatment.
Some clinical trials have demonstrated that intensive therapy with rosuvastatin or …

Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets

JWE Moss, DP Ramji - Future medicinal chemistry, 2016 - Taylor & Francis
Atherosclerosis, the primary cause of cardiovascular disease (CVD), is a chronic
inflammatory disorder in the walls of medium and large arteries. CVD is currently …

Advances in treatment strategies based on scavenging reactive oxygen species of nanoparticles for atherosclerosis

C Wu, J Mao, X Wang, R Yang, C Wang, C Li… - Journal of …, 2023 - Springer
The development of atherosclerosis (AS) is closely linked to changes in the plaque
microenvironment, which consists primarily of the cells that form plaque and the associated …

Targeting drugs to mitochondria

A Heller, G Brockhoff, A Goepferich - European journal of pharmaceutics …, 2012 - Elsevier
Mitochondria are of an increasing interest in pharmaceutical and medical research since it
has been reported that dysfunction of these organelles contributes to several diseases with …

Emerging role of radiolabeled nanoparticles as an effective diagnostic technique

ALB de Barros, A Tsourkas, B Saboury, VN Cardoso… - EJNMMI research, 2012 - Springer
Nanomedicine is emerging as a promising approach for diagnostic applications.
Nanoparticles are structures in the nanometer size range, which can present different …

Advances of nanomedicine in treatment of atherosclerosis and thrombosis

Y Mao, J Ren, L Yang - Environmental research, 2023 - Elsevier
Atherosclerosis (AS) is a chronic inflammatory vascular disease. Myocardial ischemia
originated from AS is the main cause of cardiovascular diseases, one of the major factors …

Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo

DR Lewis, LK Petersen, AW York… - Proceedings of the …, 2015 - National Acad Sciences
Atherosclerosis, the build-up of occlusive, lipid-rich plaques in arterial walls, is a focal trigger
of chronic coronary, intracranial, and peripheral arterial diseases, which together account for …