Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

Doxorubicin (DOX) is one of the most widely used anthracycline anticancer drugs due to its
high efficacy and evident antitumoral activity on several cancer types. However, its effective …

Pharmacological treatment of gliomas and other brain-infiltrating tumors remains
challenging due to limited delivery of most therapeutics across the blood–brain barrier …

Recent advances in high intensity focused ultrasound (HIFU), which was developed in the
1940s as a viable thermal tissue ablation approach, have increased its popularity. In clinics …

Ultrasound-triggered drug delivery is now becoming a mature technology with first patients
enrolling in clinical trials. Having a clear overview of the field is complicated as it mixes …

Although promising results are achieved in ultrasound mediated drug delivery, its underlying
biophysical mechanisms remain to be elucidated. Pore formation as well as endocytosis has …

It has long been shown that therapeutic ultrasound can be used effectively to ablate solid
tumors, and a variety of cancers are presently being treated in the clinic using these types of …

Glioblastoma multiforme (GBM) is a highly malignant brain tumor. The blood–brain barrier
(BBB) provides a major obstacle to chemotherapy since therapeutic doses cannot be …

This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Using conditions different from conventional medical imaging or laboratory cell lysis,
ultrasound has recently been shown to reversibly increase plasma membrane permeability …