Brainstem respiratory networks: building blocks and microcircuits
Breathing movements in mammals are driven by rhythmic neural activity generated within
spatially and functionally organized brainstem neural circuits comprising the respiratory …
spatially and functionally organized brainstem neural circuits comprising the respiratory …
[HTML][HTML] Regulation of breathing and autonomic outflows by chemoreceptors
PG Guyenet - Comprehensive Physiology, 2014 - ncbi.nlm.nih.gov
Lung ventilation fluctuates widely with behavior but arterial PCO 2 remains stable. Under
normal conditions, the chemoreflexes contribute to PaCO 2 stability by producing small …
normal conditions, the chemoreflexes contribute to PaCO 2 stability by producing small …
[HTML][HTML] Central chemoreceptors: locations and functions
E Nattie, A Li - Comprehensive physiology, 2012 - ncbi.nlm.nih.gov
Central chemoreception traditionally refers to a change in ventilation attributable to changes
in CO 2/H+ detected within the brain. Interest in central chemoreception has grown …
in CO 2/H+ detected within the brain. Interest in central chemoreception has grown …
Role of parafacial nuclei in control of breathing in adult rats
RTR Huckstepp, KP Cardoza… - Journal of …, 2015 - Soc Neuroscience
Contiguous brain regions associated with a given behavior are increasingly being divided
into subregions associated with distinct aspects of that behavior. Using recently developed …
into subregions associated with distinct aspects of that behavior. Using recently developed …
Neuromedin B-expressing neurons in the retrotrapezoid nucleus regulate respiratory homeostasis and promote stable breathing in adult mice
GMPR Souza, DS Stornetta, Y Shi, E Lim… - Journal of …, 2023 - Soc Neuroscience
Respiratory chemoreceptor activity encoding arterial Pco2 and Po2 is a critical determinant
of ventilation. Currently, the relative importance of several putative chemoreceptor …
of ventilation. Currently, the relative importance of several putative chemoreceptor …
Proton detection and breathing regulation by the retrotrapezoid nucleus
PG Guyenet, DA Bayliss, RL Stornetta… - The Journal of …, 2016 - Wiley Online Library
We discuss recent evidence which suggests that the principal central respiratory
chemoreceptors are located within the retrotrapezoid nucleus (RTN) and that RTN neurons …
chemoreceptors are located within the retrotrapezoid nucleus (RTN) and that RTN neurons …
Pre‐Bötzinger complex receives glutamatergic innervation from galaninergic and other retrotrapezoid nucleus neurons
G Bochorishvili, RL Stornetta… - Journal of …, 2012 - Wiley Online Library
The retrotrapezoid nucleus (RTN) contains CO2‐responsive neurons that regulate breathing
frequency and amplitude. These neurons (RTN‐Phox2b neurons) contain the transcription …
frequency and amplitude. These neurons (RTN‐Phox2b neurons) contain the transcription …
Neuromedin B expression defines the mouse retrotrapezoid nucleus
Y Shi, RL Stornetta, DS Stornetta… - Journal of …, 2017 - Soc Neuroscience
The retrotrapezoid nucleus (RTN) consists, by definition, of Phox2b-expressing,
glutamatergic, non-catecholaminergic, noncholinergic neurons located in the parafacial …
glutamatergic, non-catecholaminergic, noncholinergic neurons located in the parafacial …
Acid sensitivity and ultrastructure of the retrotrapezoid nucleus in Phox2b‐EGFP transgenic mice
RM Lazarenko, TA Milner, SD Depuy… - Journal of …, 2009 - Wiley Online Library
The retrotrapezoid nucleus (RTN) contains noncholinergic noncatecholaminergic
glutamatergic neurons that express the transcription factor Phox2b (chemically coded or “cc” …
glutamatergic neurons that express the transcription factor Phox2b (chemically coded or “cc” …
Criteria for central respiratory chemoreceptors: experimental evidence supporting current candidate cell groups
EC Gonye, DA Bayliss - Frontiers in physiology, 2023 - frontiersin.org
An interoceptive homeostatic system monitors levels of CO2/H+ and provides a
proportionate drive to respiratory control networks that adjust lung ventilation to maintain …
proportionate drive to respiratory control networks that adjust lung ventilation to maintain …