Investigations into bacterial protein glycosylation continue to progress rapidly. It is now
established that bacteria possess both N-linked and O-linked glycosylation pathways that …

Approximately one third of the world's population is infected with Mycobacterium
tuberculosis, the causative agent of tuberculosis. This bacterium has an unusual lipid-rich …

Proteins can be modified by a large variety of covalently linked saccharides. The present
review concentrates on two types, protein N‐glycosylation and protein O‐mannosylation …

The re-emergence of tuberculosis in its present-day manifestations–single, multiple and
extensive drug-resistant forms and as HIV-TB coinfections–has resulted in renewed …

Tuberculosis (TB) remains the second most common cause of death due to a single
infectious agent. The cell envelope of Mycobacterium tuberculosis (Mtb), the causative agent …

Humans have been increasingly recognized as being superorganisms, living in close
contact with a microbiota on all their mucosal surfaces. However, most studies on the human …

Pathogenic mycobacteria, in particular Mycobacterium tuberculosis, the causative agent of
tuberculosis, have the remarkable capacity to circumvent destruction within one of the most …

Protein O-mannosylation is an essential modification in fungi and animals. Different from
most other types of O-glycosylation, protein O-mannosylation is initiated in the endoplasmic …

TLR2 recognizes components of Mycobacterium tuberculosis (Mtb) and initiates responses
by APCs that influence both innate and adaptive immunity. Mtb lipoproteins are an important …

Mycobacterium tuberculosis (the causal agent of TB) has co-evolved with humans for
centuries. It infects via the airborne route and is a prototypic highly adapted intracellular …