Bone defects and periodontal disease are pathological conditions that may become
neglected diseases if not treated properly. Hydroxyapatite (HA), along with tricalcium …

Biomineralisation, the deposition of mineral onto a matrix, can be both a physiological and
pathological process. Bone formation involves the secretion of an extracellular matrix (ECM) …

Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as
hydroxyapatite, in the medial layer of the arteries. AMC shares some similarities to skeletal …

Vascular smooth muscle cell damage is a key step in inducing vascular calcification that
yields hydroxyapatite (HAP) as a major product. The effect of the shape of HAP on the …

Inflammatory cells and cytokines are known for long to worsen the development of
atherosclerotic plaques in mice, and intense efforts are today devoted to develop anti …

Chronic kidney disease (CKD) is associated with a multifactorial dysregulation of bone and
vascular calcification and closely linked to increased cardiovascular mortality and …

In this study we have fabricated porous injectable spherical scaffolds using chitosan
biopolymer, sodium tripolyphosphate (TPP) and nano-hydroxyapatite (nHA). TPP was …

Arterial calcification refers to the abnormal deposition of calcium salts in the arterial wall,
which results in vessel lumen stenosis and vascular remodeling. Studies increasingly show …

Atherosclerotic plaque calcification varies from early, diffuse microcalcifications to a bone-
like tissue formed by endochondral ossification. Recently, a paradigm has emerged …

Osteogenesis from preosteoblasts is important for bone tissue engineering. MicroRNAs are
a class of endogenous small RNA molecules that potentially modulate osteogenesis. In this …