The nasal mucosa is often the initial site of respiratory viral infection, replication, and
transmission. Understanding how infection shapes tissue-scale primary and memory …

Tuft cells have gained substantial attention over the past 10 years due to numerous reports
linking them with type 2 immunity and microorganism-sensing capacity in many mucosal …

While primarily a sensory organ, the mammalian olfactory epithelium (OE) also plays a
critical role as an immune barrier. Mechanisms governing interactions between the immune …

The olfactory mucosa is important for both the sense of smell and as a mucosal immune
barrier to the upper airway and brain. However, little is known about how the immune system …

Nasal vaccination elicits a humoral immune response that provides protection from airborne
pathogens, yet the origins and specific immune niches of antigen-specific IgA-secreting cells …

The diagnosis and treatment of sinonasal small round epithelial/neuroepithelial
malignancies depend on the expression of conventional neuroendocrine markers (NEMs) …

The nasal mucosa is frequently the initial site of respiratory viral infection, replication, and
transmission. Recent work has started to clarify the independent responses of epithelial …

Chronic rhinosinusitis (CRS) is a clinical syndrome defined by typical sinonasal symptoms
persisting for at least 12 weeks. CRS is divided into two distinct phenotypes, CRS with nasal …

Chemical senses allow animals to detect and discriminate a vast array of molecules. The
olfactory system is responsible of the detection of small volatile molecules, while water …

Airway mucociliary clearance (MCC) is a key innate defense mechanism for lung health.
Mucus concentration and biophysiochemical properties are tightly regulated by airway …