Context is an ever-present combination of discrete environmental elements capable of
influencing many psychological processes. When context is associated with an aversive …

Nitric oxide (NO) is a gaseous molecule with a large number of functions in living tissue. In
the brain, NO participates in numerous intracellular mechanisms, including synaptic …

Cognitive deficits are commonly reported by patients following treatment with
chemotherapeutic agents. Anthracycline-containing chemotherapy regimens are associated …

Adiponectin is an adipokine that has recently been under investigation for potential
neuroprotective effects in various brain disorders including Alzheimer's disease, stroke, and …

Cannabis is now one of the most commonly used illicit substances among pregnant women.
This is particularly concerning since developmental exposure to cannabinoids can elicit …

The role of the calcium-permeable AMPA receptor (CP-AMPAR) in synaptic plasticity is well
established. CP-AMPAR is believed to be recruited to synapse when the memory trace is in …

Object recognition memory (ORM) confers the ability to discriminate the familiarity of
previously encountered items. Reconsolidation is the process by which reactivated …

The prelimbic cortex (PL) and infralimbic cortex (IL) play a role in context-induced
reinstatement of heroin seeking in an animal model of drug relapse. Both the PL and IL …

Background Polyunsaturated fatty acids play a crucial role in neuronal function, and the
modification of these compounds in the brain could have an impact on neurodegenerative …

The successful treatment of substance use disorders is dependent on the establishment of a
long-term abstinent state. Relapse can be suppressed by interfering with memories of drug …