[HTML][HTML] Exploring the journey of emodin as a potential neuroprotective agent: novel therapeutic insights with molecular mechanism of action

S Mitra, J Anjum, M Muni, R Das, A Rauf, F Islam… - Biomedicine & …, 2022 - Elsevier
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …

Is emodin with anticancer effects completely innocent? Two sides of the coin

EK Akkol, II Tatlı, GŞ Karatoprak, OT Ağar, Ç Yücel… - Cancers, 2021 - mdpi.com
Simple Summary For cancer treatment, which is one of the most common and serious
diseases of our day, miraculous secondary compounds of natural resources, which cannot …

[HTML][HTML] The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers

Q Zhang, WW Chen, X Sun, D Qian… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Cancers are generally recognized as the leading cause of death and a predominant barrier
to prolonging life expectancy in both developed and developing countries. Emodin is a …

Therapeutic potential of natural products in treatment of cervical cancer: A review

SH Park, M Kim, S Lee, W Jung, B Kim - Nutrients, 2021 - mdpi.com
Cervical cancer is the fourth most common cancer among women worldwide. Though
several natural products have been reported regarding their efficacies against cervical …

Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus

AA Abdellatef, M Fathy, AESI Mohammed… - Journal of natural …, 2021 - Springer
Anthraquinones are a major class of compounds naturally occurring in Asphodelus
microcarpus. The pharmacological actions of anthraquinones in cancer cells are known to …

Physcion and physcion 8-O-β-glucopyranoside: A review of their pharmacology, toxicities and pharmacokinetics

Y Liu, S Chu, S Yang, Y Peng, S Ren, B Wen… - Chemico-biological …, 2019 - Elsevier
Anthraquinones constitute an important class of natural and synthetic compounds with a
broad scope of pharmacological including anti-bacterial, antioxidant, laxative, anti-tumor …

Therapeutic effects of natural products on cervical cancer: based on inflammatory pathways

ZW Zhou, HZ Long, SG Xu, FJ Li, Y Cheng… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a protective response of the body to an irritant. When an inflammatory
response occurs, immune cells are recruited to the injury, eliminating the irritation. The …

Physcion and physcion 8-O-β-D-glucopyranoside: natural anthraquinones with potential anticancer activities

M Adnan, A Rasul, G Hussain, MA Shah… - Current Drug …, 2021 - ingentaconnect.com
Nature has provided prodigious reservoirs of pharmacologically active compounds for drug
development since times. Physcion and physcion 8-O-β-D-glucopyranoside (PG) are …

Marine anthraquinones: pharmacological and toxicological issues

G Greco, E Turrini, E Catanzaro, C Fimognari - Marine drugs, 2021 - mdpi.com
The marine ecosystem, populated by a myriad of animals, plants, and microorganisms, is an
inexhaustible reservoir of pharmacologically active molecules. Among the multiple …

Preparation, characterization, and evaluation of physcion nanoparticles for enhanced oral bioavailability: An attempt to improve its antioxidant and anticancer potential

F Khuda, I Zahir, AAK Khalil, S Ali, N Ullah… - ACS …, 2023 - ACS Publications
This study aims to enhance the dissolution rate of a poorly water-soluble drug physcion by
producing its nanoparticles (NPs) using an antisolvent precipitation with a syringe pump …