Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …

Interpreting results from deprescribing interventions to generate actionable evidence is
challenging owing to inconsistent and heterogeneous outcome definitions between studies …

Purpose The complex combination of medicines associated with age-related physiological
alterations leads older adults to experience drug-related problems (DRPs). The goal of this …

Objective To identify and characterise activities for deprescribing used in general practice
and to map the identified activities to pioneering principles of deprescribing. Setting Primary …

This manuscript describes the rationale and protocol of a school-based randomized
controlled trial called “Cycling and Walk to School”(PACO, by its Spanish acronym) that aims …

Polypharmacy is common in older adults and is associated with adverse drug events,
cognitive and functional impairment, increased healthcare costs, and increased risk of frailty …

Abstract Background Electronic Medical Records (EMRs) are a rich data source to measure
and improve quality of care. As Canadian primary health care (PHC) EMRs mature, there is …

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Abstract Background Potentially inappropriate medications (PIMs) are medications whereby
the harms may outweigh the benefits for a given individual. Although overprescribed to older …

Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …