Anosmia in COVID-19: underlying mechanisms and assessment of an olfactory route to brain infection

R Butowt, CS von Bartheld - The Neuroscientist, 2021 - journals.sagepub.com
In recent months it has emerged that the novel coronavirus—responsible for the COVID-19
pandemic—causes reduction of smell and taste in a large fraction of patients. The …

Prevalence of chemosensory dysfunction in COVID-19 patients: a systematic review and meta-analysis reveals significant ethnic differences

CS von Bartheld, MM Hagen… - ACS chemical …, 2020 - ACS Publications
A significant proportion of people who test positive for COVID-19 have chemosensory
deficits. However, the reported prevalence of these deficits in smell and taste varies widely …

[HTML][HTML] Late complications of COVID-19; a systematic review of current evidence

SA SeyedAlinaghi, AM Afsahi… - Archives of academic …, 2021 - ncbi.nlm.nih.gov
Methods: This study was a systematic review of current evidence conducted in November
2020 to investigate probable late and long-term complications of COVID-19. We performed a …

Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India

A Srivastava, A Bandopadhyay, D Das… - Frontiers in …, 2020 - frontiersin.org
Studies on host-pathogen interaction have identified human ACE2 as a host cell receptor
responsible for mediating infection by coronavirus (COVID-19). Subsequent studies have …

The D614G virus mutation enhances anosmia in COVID-19 patients: evidence from a systematic review and meta-analysis of studies from South Asia

CS von Bartheld, MM Hagen… - ACS Chemical …, 2021 - ACS Publications
The prevalence of chemosensory dysfunction in patients with COVID-19 varies greatly
between populations. It is unclear whether such differences are due to factors at the level of …

Genetic susceptibility of COVID-19: a systematic review of current evidence

SA SeyedAlinaghi, M Mehrtak, M MohsseniPour… - European Journal of …, 2021 - Springer
Introduction While COVID-19 pandemic continues to spread worldwide, researchers have
linked patterns of traits to poor disease outcomes. Risk factors for COVID-19 include asthma …

Genetic hypothesis and pharmacogenetics side of renin-angiotensin-system in COVID-19

D Gemmati, V Tisato - Genes, 2020 - mdpi.com
The importance of host genetics and demography in coronavirus disease 2019 (COVID-19)
is a crucial aspect of infection, prognosis and associated case fatality rate. Individual genetic …

Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein

M Calcagnile, P Forgez, A Iannelli, C Bucci, M Alifano… - Biochimie, 2021 - Elsevier
There is increasing evidence that ACE2 gene polymorphism can modulate the interaction
between ACE2 and the SARS-CoV-2 spike protein affecting the viral entry into the host cell …

Analysis of ACE2 genetic variants in 131 Italian SARS-CoV-2-positive patients

A Novelli, M Biancolella, P Borgiani, D Cocciadiferro… - Human genomics, 2020 - Springer
Abstract Background Coronaviruses (CoV) are a large family of viruses that are common in
humans and many animal species. Animal coronaviruses rarely infect humans with the …

The complexity of SARS-CoV-2 infection and the COVID-19 pandemic

MK da Silva Torres, CDA Bichara… - Frontiers in …, 2022 - frontiersin.org
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …