Mechanisms of cancer resistance in long-lived mammals

A Seluanov, VN Gladyshev, J Vijg… - Nature Reviews Cancer, 2018 - nature.com
Cancer researchers have traditionally used the mouse and the rat as staple model
organisms. These animals are very short-lived, reproduce rapidly and are highly prone to …

Evolution and diversity of transposable elements in vertebrate genomes

CG Sotero-Caio, RN Platt, A Suh… - Genome biology and …, 2017 - academic.oup.com
Transposable elements (TEs) are selfish genetic elements that mobilize in genomes via
transposition or retrotransposition and often make up large fractions of vertebrate genomes …

Inbreeding depression explains killer whale population dynamics

M Kardos, Y Zhang, KM Parsons, H Kang… - Nature Ecology & …, 2023 - nature.com
Understanding the factors that cause endangered populations to either grow or decline is
crucial for preserving biodiversity. Conservation efforts often address extrinsic threats, such …

The critically endangered vaquita is not doomed to extinction by inbreeding depression

JA Robinson, CC Kyriazis, SF Nigenda-Morales… - Science, 2022 - science.org
In cases of severe wildlife population decline, a key question is whether recovery efforts will
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …

Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits

L Chen, Q Qiu, YU Jiang, K Wang, Z Lin, Z Li, F Bibi… - Science, 2019 - science.org
INTRODUCTION The ruminants are one of the most successful mammalian lineages,
exhibiting extensive morphological and ecological diversity and containing several key …

Contentious relationships in phylogenomic studies can be driven by a handful of genes

XX Shen, CT Hittinger, A Rokas - Nature ecology & evolution, 2017 - nature.com
Phylogenomic studies have resolved countless branches of the tree of life, but remain
strongly contradictory on certain, contentious relationships. Here, we use a maximum …

Phylogenomic resolution of the cetacean tree of life using target sequence capture

MR McGowen, G Tsagkogeorga… - Systematic …, 2020 - academic.oup.com
The evolution of cetaceans, from their early transition to an aquatic lifestyle to their
subsequent diversification, has been the subject of numerous studies. However, although …

Interrogating genomic-scale data for Squamata (lizards, snakes, and amphisbaenians) shows no support for key traditional morphological relationships

FT Burbrink, FG Grazziotin, RA Pyron… - Systematic …, 2020 - academic.oup.com
Genomics is narrowing uncertainty in the phylogenetic structure for many amniote groups.
For one of the most diverse and species-rich groups, the squamate reptiles (lizards, snakes …

The contribution of historical processes to contemporary extinction risk in placental mammals

AP Wilder, MA Supple, A Subramanian, A Mudide… - Science, 2023 - science.org
Species persistence can be influenced by the amount, type, and distribution of diversity
across the genome, suggesting a potential relationship between historical demography and …

Convergent regulatory evolution and loss of flight in paleognathous birds

TB Sackton, P Grayson, A Cloutier, Z Hu, JS Liu… - Science, 2019 - science.org
A core question in evolutionary biology is whether convergent phenotypic evolution is driven
by convergent molecular changes in proteins or regulatory regions. We combined …