Natural polymers for the microencapsulation of cells

L Gasperini, JF Mano, RL Reis - Journal of the royal …, 2014 - royalsocietypublishing.org
The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an
attractive procedure for many biomedical and biotechnological applications, such as …

Hydrogels in emerging technologies for type 1 diabetes

S Fuchs, AU Ernst, LH Wang, K Shariati… - Chemical …, 2020 - ACS Publications
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

Q Liu, A Chiu, LH Wang, D An, M Zhong… - Nature …, 2019 - nature.com
Foreign body reaction (FBR) to implanted biomaterials and medical devices is common and
can compromise the function of implants or cause complications. For example, in cell …

Polymers in cell encapsulation from an enveloped cell perspective

P de Vos, HA Lazarjani, D Poncelet… - Advanced drug delivery …, 2014 - Elsevier
In the past two decades, many polymers have been proposed for producing
immunoprotective capsules. Examples include the natural polymers alginate, agarose …

Cell encapsulation via microtechnologies

AR Kang, JS Park, J Ju, GS Jeong, SH Lee - Biomaterials, 2014 - Elsevier
The encapsulation of living cells in a variety of soft polymers or hydrogels is important,
particularly, for the rehabilitation of functional tissues capable of repairing or replacing …

Microcapsules and microcarriers for in situ cell delivery

RM Hernández, G Orive, A Murua, JL Pedraz - Advanced drug delivery …, 2010 - Elsevier
In recent years, the use of transplanted living cells pumping out active factors directly at the
site has proven to be an emergent technology. However a recurring impediment to rapid …

Cell microencapsulation technology: towards clinical application

A Murua, A Portero, G Orive, RM Hernández… - Journal of controlled …, 2008 - Elsevier
The pharmacokinetic properties of a drug can be significantly improved by the delivery
process. Scientists have understood that developing suitable drug delivery systems that …

Microcarriers in application for cartilage tissue engineering: Recent progress and challenges

SL Ding, X Liu, XY Zhao, KT Wang, W Xiong, ZL Gao… - Bioactive Materials, 2022 - Elsevier
Successful regeneration of cartilage tissue at a clinical scale has been a tremendous
challenge in the past decades. Microcarriers (MCs), usually used for cell and drug delivery …

Multiscale requirements for bioencapsulation in medicine and biotechnology

P de Vos, M Bučko, P Gemeiner, M Navrátil, J Švitel… - Biomaterials, 2009 - Elsevier
Bioencapsulation involves the envelopment of tissues or biological active substances in
semipermeable membranes. Bioencapsulation has been shown to be efficacious in …

Microfluidic-based synthesis of hydrogel particles for cell microencapsulation and cell-based drug delivery

J Wan - Polymers, 2012 - mdpi.com
Encapsulation of cells in hydrogel particles has been demonstrated as an effective approach
to deliver therapeutic agents. The properties of hydrogel particles, such as the chemical …