The pyridazine ring is endowed with unique physicochemical properties, characterized by
weak basicity, a high dipole moment that subtends π-π stacking interactions and robust …

The review is devoted to recent advances in the chemistry of pyridazine—a six-membered
heterocycle containing two nitrogen atoms in adjacent positions. The practical significance …

Most breast and prostate tumors are hormone-dependent, making it possible to use
hormone therapy in patients with these tumors. The design of effective endocrine drugs that …

A new class of pyridazine-based binuclear nickel (II), copper (II) and zinc (II) complexes of
the type [M2 (L1–3) 2](NO3) 2 (1–9) with tridentate Schiff base ligands 3-chloro-6 …

A visible-light-promoted electron-donor–acceptor (EDA) complex-initiated [5+ 1] annulation
between biguanides and perfluoroalkyl halides for the construction of perfluoroalkyl-s …

An approach to steroids annulated with pyridazines via cascade imination/electrocyclization
of chlorovinyl aldehydes with oxamic acid thiohydrazides is disclosed. A mechanistic …

A flexible approach to previously unknown spirofused and linked 1, 3, 4-thiadiazine
derivatives of steroids with selective control of heterocyclization patterns is disclosed.(N …

An interesting self-coupling/cyclization of 5-aminopyrazoles is revealed, which provides a
variety of pyridazine cores in reasonable yields. In this reaction, C (sp2)–C (sp2) and N–N …

A novel approach to the synthesis of 3, 4-dicarbonyl-substituted pyrazoles from a wide range
of 1, 3-dicarbonyl compounds and oxamic acid thiohydrazides was developed via iodine …

A facile and efficient strategy for the synthesis of 1, 4-dihydropyridazines and pyridazines
through I2-promoted [4+ 2] cycloaddition of in situ generated azoalkenes with enaminones …