Prions are infectious proteins and over the past few decades, some prions have become
renowned for their causative role in several neurodegenerative diseases in animals and …

Follicular dendritic cells are mesenchymal-derived dendritic cells located in the B follicles,
where they capture, retain and present antigens to surrounding B cells, thus playing a …

Prion diseases are sub-acute neurodegenerative diseases that affect humans and some
domestic and free-ranging animals. Infectious prion agents are considered to comprise …

Prion diseases are infectious neurodegenerative disorders characterized by accumulations
of abnormally folded cellular prion protein in affected tissues. Many natural prion diseases …

Prion diseases are a unique group of infectious chronic neurodegenerative disorders to
which there are no cures. Although prion infections do not stimulate adaptive immune …

Numerous studies have investigated the cellular prion protein (PrP C) since its discovery.
These investigations have explained that its structure is predominantly composed of alpha …

The cellular prion protein (PrPC), a cell surface glycoprotein originally identified for its
central role in prion diseases (also called transmissible spongiform encephalopathies), has …

Prion diseases are fatal neurodegenerative processes caused by the accumulation of the
pathological prion protein, PrPSc. While pathological lesions are limited to the central …

In peripherally acquired prion diseases, prions move through several tissues of the infected
host, notably in the lymphoid tissue, long before the occurrence of neuroinvasion …

Bovine spongiform encephalopathy (BSE) created a global European crisis in the 1980s
and 90s, with very serious health and economic implications. Classical BSE now appears to …