Methods of generating dielectrophoretic force for microfluidic manipulation of bioparticles

EA Kwizera, M Sun, AM White, J Li… - ACS biomaterials science …, 2021 - ACS Publications
Manipulation of microscale bioparticles including living cells is of great significance to the
broad bioengineering and biotechnology fields. Dielectrophoresis (DEP), which is defined …

The latest advances on nonlinear insulator-based electrokinetic microsystems under direct current and low-frequency alternating current fields: a review

BH Lapizco-Encinas - Analytical and Bioanalytical Chemistry, 2022 - Springer
This review article presents an overview of the evolution of the field of insulator-based
dielectrophoresis (iDEP); in particular, it focuses on insulator-based electrokinetic (iEK) …

Electrokinetically driven exosome separation and concentration using dielectrophoretic-enhanced PDMS-based microfluidics

S Ayala-Mar, VH Perez-Gonzalez… - Analytical …, 2019 - ACS Publications
Exosomes are a specific subpopulation of extracellular vesicles that have gained interest
because of their many potential biomedical applications. However, exosome isolation and …

Microfluidic screening of electric fields for electroporation

PA Garcia, Z Ge, JL Moran, CR Buie - Scientific reports, 2016 - nature.com
Electroporation is commonly used to deliver molecules such as drugs, proteins, and/or DNA
into cells, but the mechanism remains poorly understood. In this work a rapid microfluidic …

Rapid determination of the electroporation threshold for bacteria inactivation using a lab-on-a-chip platform

T Wang, H Chen, C Yu, X Xie - Environment international, 2019 - Elsevier
Electroporation based locally enhanced electric field treatment (LEEFT) is an emerging
bacteria inactivation technology for drinking water disinfection. Nevertheless, the lethal …

Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis

J Ding, RM Lawrence, PV Jones, BG Hogue, MA Hayes - Analyst, 2016 - pubs.rsc.org
Biotechnology, separation science, and clinical research are impacted by microfluidic
devices. Separation and manipulation of bioparticles such as DNA, protein and viruses are …

Refinement of insulator-based dielectrophoresis

CV Crowther, MA Hayes - Analyst, 2017 - pubs.rsc.org
The ability to separate analytes with increasingly similar properties drives the field of
separation science. One way to achieve such separations is using trapping and streaming …

Isolation and identification of Listeria monocytogenes utilizing DC insulator-based dielectrophoresis

CV Crowther, SH Hilton, LK Kemp, MA Hayes - Analytica chimica acta, 2019 - Elsevier
Foodborne pathogens pose one of the greatest challenges facing public health in the
modern day. One important pathogen, Listeria monocytogenes, is known to be challenging …

Experimental and theoretical study of dielectrophoretic particle trapping in arrays of insulating structures: Effect of particle size and shape

MA Saucedo‐Espinosa, BH Lapizco‐Encinas - Electrophoresis, 2015 - Wiley Online Library
Insulator‐based dielectrophoresis (iDEP) employs insulating structures embedded in a
microchannel to produce electric field gradients. This contribution presents a detailed …

Differentiation of Escherichia coli serotypes using DC gradient insulator dielectrophoresis

PV Jones, AF DeMichele, LK Kemp… - Analytical and bioanalytical …, 2014 - Springer
Bacteria play a significant role in both human health and disease. An estimated 9.4 million
cases of foodborne illness occur in the United States each year. As a result, rapid …