GM-CSF, IL-3, and IL-5 family of cytokines: regulators of inflammation
M Dougan, G Dranoff, SK Dougan - Immunity, 2019 - cell.com
The β common chain cytokines GM-CSF, IL-3, and IL-5 regulate varied inflammatory
responses that promote the rapid clearance of pathogens but also contribute to pathology in …
responses that promote the rapid clearance of pathogens but also contribute to pathology in …
Insights into cytokine–receptor interactions from cytokine engineering
Cytokines exert a vast array of immunoregulatory actions critical to human biology and
disease. However, the desired immunotherapeutic effects of native cytokines are often …
disease. However, the desired immunotherapeutic effects of native cytokines are often …
The GM–CSF/IL‐3/IL‐5 cytokine receptor family: from ligand recognition to initiation of signaling
SE Broughton, U Dhagat, TR Hercus… - Immunological …, 2012 - Wiley Online Library
Granulocyte–macrophage colony‐stimulating factor (GM–CSF), interleukin‐3 (IL‐3), and IL‐
5 are members of a discrete family of cytokines that regulates the growth, differentiation …
5 are members of a discrete family of cytokines that regulates the growth, differentiation …
Allergic diseases: From bench to clinic-Contribution of the discovery of interleukin-5
T Yanagibashi, M Satoh, Y Nagai, M Koike, K Takatsu - Cytokine, 2017 - Elsevier
T helper 2 cells produce a number of cytokines including inteleukin (IL)-5, IL-4 and IL-13.
Group 2 innate lymphoid cells (ILC2s) also produce IL-5 under sterile conditions. IL-5 is …
Group 2 innate lymphoid cells (ILC2s) also produce IL-5 under sterile conditions. IL-5 is …
OGlcNAcylation and phosphorylation have opposing structural effects in tau: phosphothreonine induces particular conformational order
MA Brister, AK Pandey, AA Bielska… - Journal of the American …, 2014 - ACS Publications
Phosphorylation and OGlcNAcylation are dynamic intracellular protein post-translational
modifications that frequently are alternatively observed on the same serine and threonine …
modifications that frequently are alternatively observed on the same serine and threonine …
IL-3 in the development and function of basophils
The β common chain (βc) cytokine family includes granulocyte-macrophage colony-
stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5, all of which use βc as key …
stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5, all of which use βc as key …
Signalling by the βc family of cytokines
Abstract The GM-CSF, IL-3 and IL-5 family of cytokines, also known as the βc family due to
their receptors sharing the signalling subunit βc, regulates multiple biological processes …
their receptors sharing the signalling subunit βc, regulates multiple biological processes …
The βc receptor family–Structural insights and their functional implications
Granulocyte–macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5
are members of a small family of cytokines that share a beta receptor subunit (βc). These …
are members of a small family of cytokines that share a beta receptor subunit (βc). These …
A miniature protein stabilized by a cation− π interaction network
The design of folded miniature proteins is predicated on establishing noncovalent
interactions that direct the self-assembly of discrete thermostable tertiary structures. In this …
interactions that direct the self-assembly of discrete thermostable tertiary structures. In this …
Role of the β Common (βc) Family of Cytokines in Health and Disease
TR Hercus, WLT Kan, SE Broughton… - Cold Spring …, 2018 - cshperspectives.cshlp.org
The β common ([βc]/CD131) family of cytokines comprises granulocyte macrophage colony-
stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5, all of which use βc as their key …
stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5, all of which use βc as their key …