Chronic stress and high levels of glucocorticoids produce functional and structural changes
in brain and especially in the hippocampus, an important limbic system structure that plays a …

The increasing morbidity rates of brain disorders and conditions such as anxiety,
depression, Alzheimer's disease, and Parkinson's disease have become a severe problem …

Exercise has been shown to have beneficial effects on brain functions in humans and
animals. Exercise can improve memory and learning in age-related neurodegenerative …

Major depressive disorder (MDD) is a prevalent psychiatric disorder that brings great harm
and burden to both patients and society. This study aimed to examine the effects of whole …

Gardenia yellow pigment (GYP) is a natural food coloring agent with a variety of
pharmacological activities. However, the applications of GYP are limited due to its poor …

Diabetes increases the likelihood of developing depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …

Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

Psychotropic effect of Crocus sativus L.(family Iridaceae) biologically active chemical
compounds are quite well documented and they can therefore be used in addition to the …

Depression is a common non-motor symptom in patients with Parkinson's disease (PD) and
difficult to treat. Crocin is a natural multipotential neuroprotective compound that has been …

Introduction Adult hippocampal neurogenesis (AHN) is acknowledged to play a critical role
in depression. Emerging evidence suggests that the Wnt/β-catenin pathway can modulate …