Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …
[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics
U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …
produce aggressive malignancies that causes millions of deaths every year. With the new …
Plant secondary metabolites as anticancer agents: successes in clinical trials and therapeutic application
AML Seca, DCGA Pinto - International journal of molecular sciences, 2018 - mdpi.com
Cancer is a multistage process resulting in an uncontrolled and abrupt division of cells and
is one of the leading causes of mortality. The cases reported and the predictions for the near …
is one of the leading causes of mortality. The cases reported and the predictions for the near …
Alkaloids for cancer prevention and therapy: Current progress and future perspectives
A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …
[HTML][HTML] Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids
AQ Khan, K Rashid, AA AlAmodi, MV Agha… - Biomedicine & …, 2021 - Elsevier
Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of
human diseases including cancer. In this line, now it has become evident that ROS …
human diseases including cancer. In this line, now it has become evident that ROS …
[HTML][HTML] Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment
Anticancer drugs are a group of therapeutic agents used to enhance cell death in targeted
cell types of neoplasia. Because of frequent use and eventual discharge, they have been …
cell types of neoplasia. Because of frequent use and eventual discharge, they have been …
Plants as a source of anticancer agents: From bench to bedside
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
Plant Derived Bioactive Compounds, Their Anti-Cancer Effects and In Silico Approaches as an Alternative Target Treatment Strategy for Breast Cancer: An Updated …
V Shrihastini, P Muthuramalingam, S Adarshan… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is one of the leading causes of death among women
worldwide. Breast cancer may be provoked due to several physical, chemical and …
worldwide. Breast cancer may be provoked due to several physical, chemical and …
Alkaloid from Geissospermum sericeum Benth. & Hook.f. ex Miers (Apocynaceae) Induce Apoptosis by Caspase Pathway in Human Gastric Cancer Cells
ML Carmo Bastos, JV Silva-Silva, J Neves Cruz… - Pharmaceuticals, 2023 - mdpi.com
Gastric cancer is among the major causes of death from neoplasia leading causes of death
worldwide, with high incidence rates and problems related to its treatment. Here, we outline …
worldwide, with high incidence rates and problems related to its treatment. Here, we outline …
Recent advances in improved anticancer efficacies of camptothecin nano-formulations: A systematic review
M Ghanbari-Movahed, T Kaceli, A Mondal, MH Farzaei… - Biomedicines, 2021 - mdpi.com
Camptothecin (CPT), a natural plant alkaloid, has indicated potent antitumor activities via
targeting intracellular topoisomerase I. The promise that CPT holds in therapies is restricted …
targeting intracellular topoisomerase I. The promise that CPT holds in therapies is restricted …