Target identification is the first step in the drug and vaccine discovery process; in silico
subtractive genomics is widely used in this process. Using this approach, in recent years, a …

Vaccination stands alone as an unparalleled medical intervention able to save human lives
numbering hundreds of millions. Modern licensed vaccines are either whole organism …

Bacterial enteric infections resulting in diarrhea, dysentery, or enteric fever constitute a huge
public health problem, with more than a billion episodes of disease annually in developing …

Mycobacterium abscessus, a non-tuberculous rapidly growing mycobacterium, is
recognized as an emerging human pathogen causing a variety of infections ranging from …

Integrative genomics predictors, which score highly in predicting bacterial essential genes,
would be unfeasible in most species because the data sources are limited. We developed a …

Infectious diseases are the leading causes of death worldwide. Hence, there is a need to
develop new antimicrobial agents. Traditional method of drug discovery is time consuming …

Mycoplasma genitalium infection is a sexually transmitted infection that causes urethritis,
cervicitis, and pelvic inflammatory disease (PID) in men and women. The global rise in …

Mycobacterium ulcerans, the causative agent of Buruli ulcer, is the third most common
mycobacterial disease after tuberculosis and leprosy. The present treatment options are …

Essential proteins are indispensable to support cellular life. Identifying essential proteins
can help us understand the minimal requirements for cell survival, which plays a significant …

Sexually transmitted infections (STIs) are caused by a wide variety of bacteria, viruses, and
parasites that are transmitted from one person to another primarily by vaginal, anal, or oral …