Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches
B Zeng, A Wei, Q Zhou, M Yuan, K Lei… - Phytotherapy …, 2022 - Wiley Online Library
Abstract Andrographis paniculata (Burm. f.) Wall. ex Nees, a renowned herb medicine in
China, is broadly utilized in traditional Chinese medicine (TCM) for the treatment of cold and …
China, is broadly utilized in traditional Chinese medicine (TCM) for the treatment of cold and …
Self-assembly of amphiphilic compounds as a versatile tool for construction of nanoscale drug carriers
R Kashapov, G Gaynanova, D Gabdrakhmanov… - International Journal of …, 2020 - mdpi.com
This review focuses on synthetic and natural amphiphilic systems prepared from straight-
chain and macrocyclic compounds capable of self-assembly with the formation of nanoscale …
chain and macrocyclic compounds capable of self-assembly with the formation of nanoscale …
Formulation of nanomicelles to improve the solubility and the oral absorption of silymarin
Two novel nanomicellar formulations were developed to improve the poor aqueous
solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and …
solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and …
Chitosan coated human serum albumin nanoparticles: A promising strategy for nose-to-brain drug delivery
The aim of the present study was the development of human serum albumin nanoparticles
(HSA NPs) as nose-to-brain carrier. To strengthen, the efficacy of nanoparticles as drug …
(HSA NPs) as nose-to-brain carrier. To strengthen, the efficacy of nanoparticles as drug …
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
Aim The aim of this study was to improve the therapeutic index of chemotherapeutic drugs
on glioblastoma cells through an improved co-drug delivery system. Materials and methods …
on glioblastoma cells through an improved co-drug delivery system. Materials and methods …
Anticancer potential of andrographolide from Andrographis paniculata (Burm. f.) Nees and its mechanisms of action
Z Malik, R Parveen, B Parveen, S Zahiruddin… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Synthetic drugs used for cancer treatment have side
effects that may be immunosupressive, can cause liver, kidney and cardiac toxicity, and …
effects that may be immunosupressive, can cause liver, kidney and cardiac toxicity, and …
Modulation of engineered nanomaterial interactions with organ barriers for enhanced drug transport
V Lenders, X Koutsoumpou, P Phan… - Chemical Society …, 2023 - pubs.rsc.org
The biomedical use of nanoparticles (NPs) has been the focus of intense research for over a
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …
[HTML][HTML] Novel wine in an old bottle: Preventive and therapeutic potentials of andrographolide in atherosclerotic cardiovascular diseases
T Gou, M Hu, M Xu, Y Chen, R Chen, T Zhou… - Journal of …, 2023 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) frequently results in sudden death and
poses a serious threat to public health worldwide. The drugs approved for the prevention …
poses a serious threat to public health worldwide. The drugs approved for the prevention …
Recent advancements in liposome-targeting strategies for the treatment of gliomas: a systematic review
J Li, T Tan, L Zhao, M Liu, Y You, Y Zeng… - ACS Applied Bio …, 2020 - ACS Publications
Malignant tumors represent some of the most intractable diseases that endanger human
health. A glioma is a tumor of the central nervous system that is characterized by severe …
health. A glioma is a tumor of the central nervous system that is characterized by severe …
Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation
Aripiprazole (ARP) is an antipsychotic drug approved for the treatment of schizophrenia. It is
poorly water-soluble and undergoes extensive hepatic metabolism and P-gp efflux, which …
poorly water-soluble and undergoes extensive hepatic metabolism and P-gp efflux, which …