Analgesia and sedation in critically ill pediatric patients: an update from the recent guidelines and point of view

MC Mondardini, F Sperotto, M Daverio… - European Journal of …, 2023 - Springer
In the last decades, the advancement of knowledge in analgesia and sedation for critically ill
pediatric patients has been conspicuous and relevant. Many recommendations have …

Ketamine for management of neonatal and pediatric refractory status epilepticus

M Jacobwitz, C Mulvihill, MC Kaufman, AK Gonzalez… - Neurology, 2022 - AAN Enterprises
Background and Objectives Few data are available regarding the use of anesthetic infusions
for refractory status epilepticus (RSE) in children and neonates, and ketamine use is …

Ketamine Clinical Use on the Pediatric Critically Ill Infant: A Global Bibliometric and Critical Review of Literature

MLF Maia, LVPS Pantoja, BC Da Conceição… - Journal of Clinical …, 2023 - mdpi.com
The developing central nervous system is vulnerable to several stimuli, especially
psychotropic drugs. Sedation procedures during the developmental period are frequent in …

Acute effects of ketamine on intracranial pressure in children with severe traumatic brain injury

JC Laws, EH Vance, KA Betters, JJ Anderson… - Critical care …, 2023 - journals.lww.com
OBJECTIVES: The acute cerebral physiologic effects of ketamine in children have been
incompletely described. We assessed the acute effects of ketamine on intracranial pressure …

A comparison of ketamine and midazolam as first-line anesthetic infusions for pediatric status epilepticus

M Jacobwitz, C Mulvihill, MC Kaufman, AK Gonzalez… - Neurocritical Care, 2024 - Springer
Background Pediatric refractory status epilepticus (RSE) often requires management with
anesthetic infusions, but few data compare first-line anesthetics. This study aimed to …

Is ketamine infusion effective and safe as an adjuvant of sedation in the PICU? Results from the Ketamine Infusion Sedation Study (KISS)

A Tessari, F Sperotto, F Pece… - … : The Journal of …, 2023 - Wiley Online Library
Abstract Study Objective We aimed to evaluate the efficacy and safety of ketamine in
ensuring comfort and sparing conventional drugs when used as an adjuvant for analgesia …

Trends in sedationanalgesia practices in pediatric liver transplant patients admitted postoperatively to the pediatric intensive care unit: an analysis of data from the …

M Goldstein, A Jergel, S Karpen, Z He… - Pediatric …, 2024 - Wiley Online Library
Background Children admitted to the pediatric intensive care unit (PICU), after liver
transplantation, frequently require analgesia and sedation in the immediate postoperative …

Ketamine: Pro or antiepileptic agent? A systematic review

IM Shehata, NA Kohaf, MW ElSayed, K Latifi… - Heliyon, 2024 - cell.com
Abstract Purpose of Review: This evidence-based systematic review evaluated the safety of
ketamine as regard the potential to provoke epilepsy to help better guide anesthesiologists …

Multicenter Retrospective Review of Ketamine Use in Pediatric Intensive Care Units (KetaminePICU Study)

CM Groth, CA Droege, P Sarangarm… - … Care Research and …, 2024 - Wiley Online Library
Objective. Describe continuous infusion (CI) ketamine practices in pediatric intensive care
units (PICUs) and evaluate its effect on pain/sedation scores, exposure to …

Trends in analgesiasedation of pediatric patients receiving I131 MIBG in the pediatric intensive care unit: A report from the Pediatric Health Information System …

J Dhuse, T Cash, MS Elges, A Alazraki… - Pediatric Blood & …, 2024 - Wiley Online Library
Background Children with neuroblastoma receiving I131 metaiodobenzylguanidine (MIBG)
therapy require sedationanalgesia for strict radiation safety precautions during MIBG …