[HTML][HTML] Potential of histone deacetylase inhibitors in the control and regulation of prostate, breast and ovarian cancer
SD Pramanik, A Kumar Halder, U Mukherjee… - Frontiers in …, 2022 - frontiersin.org
Histone deacetylases (HDACs) are enzymes that play a role in chromatin remodeling and
epigenetics. They belong to a specific category of enzymes that eliminate the acetyl part of …
epigenetics. They belong to a specific category of enzymes that eliminate the acetyl part of …
[HTML][HTML] Potential of synthetic and natural compounds as novel histone deacetylase inhibitors for the treatment of hematological malignancies
Simple Summary Histone deacetylases (HDACs) are epigenetic regulators that influence
chromatin structure and gene transcription, but also the function of non-histone targets like …
chromatin structure and gene transcription, but also the function of non-histone targets like …
Hydroxamic acid hybrids as the potential anticancer agents: An Overview
W Liu, Y Liang, X Si - European Journal of Medicinal Chemistry, 2020 - Elsevier
Hydroxamic acid derivatives are potential histone deacetylase inhibitors, and several
hydroxamic acid-based histone deacetylase inhibitors have already been used clinically as …
hydroxamic acid-based histone deacetylase inhibitors have already been used clinically as …
Computational studies and antimicrobial activity of 1-(benzo [d] oxazol-2-yl)-3, 5-diphenylformazan derivatives
Background: Due to the biological importance of the benzoxazole derivatives, some 1-
(benzo [d] oxazol-2-yl)-3, 5-diphenyl-formazans 4a-f were synthesized and screened for in …
(benzo [d] oxazol-2-yl)-3, 5-diphenyl-formazans 4a-f were synthesized and screened for in …
[HTML][HTML] Design, in silico studies, and synthesis of new 1, 8-naphthyridine-3-carboxylic acid analogues and evaluation of their H1R antagonism effects
New 1, 8-naphthyridine-3-carboxylic acid derivatives were designed, synthesized and
evaluated for their in vivo antihistaminic activity on guinea pig trachea by using …
evaluated for their in vivo antihistaminic activity on guinea pig trachea by using …
[PDF][PDF] In silico assessment of the role of iridoid in the treatment of Zika and influenza virus infection
Iridoids have been showing anticancer, antiproliferative, cardioprotective, hepatoprotective,
antihyperglycemic, and immune stimulatory activities. Zika and H3N2 viruses belong to the …
antihyperglycemic, and immune stimulatory activities. Zika and H3N2 viruses belong to the …
[PDF][PDF] Antifungal and antibacterial activities of phenyl and ortho hydroxyl phenyl linked imidazolyl triazolo hydroxamic acid derivatives
Synthesized molecules (FP1-FP12) were evaluated against five fungal species as Candida
albicans, Candida glabrata, Candida paropsialis, Candida tropicalis SSKM, Aspergillus …
albicans, Candida glabrata, Candida paropsialis, Candida tropicalis SSKM, Aspergillus …
Hydroxyacetamide derivatives: cytotoxicity, genotoxicity, antioxidative and metal chelating studies
Cancer is one of the most life threatening noncommunicable diseases of mankind. In India, it
has been estimated to have have caused 8.8 lakh deaths in 2016 alone, and 1.74 million …
has been estimated to have have caused 8.8 lakh deaths in 2016 alone, and 1.74 million …
Indazole derivatives effective against gastrointestinal diseases
Background: In this fast-growing lifestyle, humans are in the race against time to cope up
with busy schedule. Less exercise, consumption of high calorie-low fiber food and stress …
with busy schedule. Less exercise, consumption of high calorie-low fiber food and stress …
[PDF][PDF] Novel Cinnamic Acid Derivatives as Potential Anticancer Agents: Synthesis, In Vitro Cytotoxicity and Molecular Docking Studies
Inhibition of matrix metalloproteinase-9 (MMP-9) can be an emerging strategy for a cancer
cure as overexpression of MMP-9 is associated with several types of malignancies …
cure as overexpression of MMP-9 is associated with several types of malignancies …