Brain cells normally respond adaptively to bioenergetic challenges resulting from ongoing
activity in neuronal circuits, and from environmental energetic stressors such as food …

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. It is typically
fatal within 2–5 years of symptom onset. The incidence of ALS is largely uniform across most …

Mitochondrial dysfunction is reiteratively involved in the pathogenesis of diverse
neurodegenerative diseases. Current in vitro and in vivo approaches support that …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by
progressive muscular paralysis reflecting degeneration of motor neurones in the primary …

Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …

Amyotrophic lateral sclerosis (ALS) is characterised by the progressive degeneration of
upper and lower motor neurons. Besides motor neuron degeneration, ALS is associated …

Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder
primarily characterized by selective degeneration of both the upper motor neurons in the …

The main aims in the care of individuals with amyotrophic lateral sclerosis (ALS) are to
minimize morbidity and maximize quality of life. Although no cure exists for ALS, supportive …

Background: Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative
motor neuron disease in adults, characterized by upper and lower motor neuron …