The neural basis of psychedelic action
Psychedelics are serotonin 2A receptor agonists that can lead to profound changes in
perception, cognition and mood. In this review, we focus on the basic neurobiology …
perception, cognition and mood. In this review, we focus on the basic neurobiology …
[HTML][HTML] Canalization and plasticity in psychopathology
RL Carhart-Harris, S Chandaria, DE Erritzoe… - …, 2023 - Elsevier
This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …
model of a general factor of psychopathology. To achieve this, we have distinguished …
Human brain effects of DMT assessed via EEG-fMRI
C Timmermann, L Roseman… - Proceedings of the …, 2023 - National Acad Sciences
Psychedelics have attracted medical interest, but their effects on human brain function are
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …
Pivotal mental states
A Brouwer, RL Carhart-Harris - Journal of …, 2021 - journals.sagepub.com
This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …
plastic state aiding rapid and deep learning that can mediate psychological transformation …
[HTML][HTML] From many to (n) one: Meditation and the plasticity of the predictive mind
RE Laukkonen, HA Slagter - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
How profoundly can humans change their own minds? In this paper we offer a unifying
account of deconstructive meditation under the predictive processing view. We start from …
account of deconstructive meditation under the predictive processing view. We start from …
In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape
To understand how pharmacological interventions can exert their powerful effects on brain
function, we need to understand how they engage the brain's rich neurotransmitter …
function, we need to understand how they engage the brain's rich neurotransmitter …
[HTML][HTML] Phenomenology and content of the inhaled N, N-dimethyltryptamine (N, N-DMT) experience
Understanding the phenomenology and content of the inhaled N, N, dimethyltryptamine (N,
N-DMT) experience is critical to facilitate and support ongoing research and therapeutic …
N-DMT) experience is critical to facilitate and support ongoing research and therapeutic …
[HTML][HTML] Does psychedelic therapy have a transdiagnostic action and prophylactic potential?
R Kočárová, J Horáček, R Carhart-Harris - Frontiers in Psychiatry, 2021 - frontiersin.org
Addressing global mental health is a major 21st-century challenge. Current treatments have
recognized limitations; in this context, new ones that are prophylactic and effective across …
recognized limitations; in this context, new ones that are prophylactic and effective across …
[HTML][HTML] More than meets the eye: The role of sensory dimensions in psychedelic brain dynamics, experience, and therapeutics
Psychedelics are undergoing a major resurgence of scientific and clinical interest. While
multiple theories and frameworks have been proposed, there is yet no universal agreement …
multiple theories and frameworks have been proposed, there is yet no universal agreement …
Distinct roles of forward and backward alpha-band waves in spatial visual attention
A Alamia, L Terral, MR D'ambra, R VanRullen - Elife, 2023 - elifesciences.org
Previous research has associated alpha-band [8–12 Hz] oscillations with inhibitory
functions: for instance, several studies showed that visual attention increases alpha-band …
functions: for instance, several studies showed that visual attention increases alpha-band …