Biological applications of Schiff bases: An overview
SK Raju, A Settu, A Thiyagarajan… - GSC Biological and …, 2022 - gsconlinepress.com
Schiff bases are the compounds containing the azomethine group (-HC= N-). They are
formed by the condensation of ketones or aldehydes with a primary amine. Formation of …
formed by the condensation of ketones or aldehydes with a primary amine. Formation of …
Molecular dynamics simulation, QSAR, DFT, molecular docking, ADMET, and synthesis of ethyl 3-((5-Bromopyridin-2-yl) Imino) butanoate analogues as potential …
Abstract Structural modifications of ethyl-3-((5-bromopyridin-2-yl) imino) butanoate ester
enhances its biological activities. In the present work, the synthesis of a Schiff base by …
enhances its biological activities. In the present work, the synthesis of a Schiff base by …
Synthesis and characterization of two new mixed‐ligand Cu (II) complexes of a tridentate NN'O type Schiff base ligand and N‐donor heterocyclic co‐ligands: In vitro …
Two new mixed‐ligand complexes with general formula [Cu (SB)(L')] ClO4 (1 and 2) were
synthesized and characterized by different spectroscopic and analytical techniques …
synthesized and characterized by different spectroscopic and analytical techniques …
[HTML][HTML] Synthesis and characterization of novel hydrazone derivatives of isonicotinic hydrazide and their evaluation for antibacterial and cytotoxic potential
Hydrazones are active compounds having an azomethine–NHN= CH group and are widely
studied owing to their ease of preparation and diverse pharmacological benefits. Novel …
studied owing to their ease of preparation and diverse pharmacological benefits. Novel …
Synthesis and computational investigation of N, N-dimethyl-4-[(Z)-(phenylimino) methyl] aniline derivatives: Biological and quantitative structural activity relationship …
I Waziri, MT Kelani, MO Oyedeji-Amusa… - Journal of Molecular …, 2023 - Elsevier
This study describes the synthesis, characterisation and biological activities of four Schiff
base compounds, namely: N, N-dimethyl-4-(((4-nitrophenyl) imino) methyl) aniline (ABS1), 4 …
base compounds, namely: N, N-dimethyl-4-(((4-nitrophenyl) imino) methyl) aniline (ABS1), 4 …
[HTML][HTML] Synthesis, in-vitro and in-silico antibacterial and computational studies of selected thiosemicarbazone-benzaldehyde derivatives as potential antibiotics
Three new Schiff bases,(Z)-2-(4-(dimethylamino) benzylidene)-N-
methylhydrazinecarbothioamide (PDM),(Z)-2-(2-hydroxy-5-nitrobenzylidene)-N …
methylhydrazinecarbothioamide (PDM),(Z)-2-(2-hydroxy-5-nitrobenzylidene)-N …
[PDF][PDF] Synthetic approaches of medicinally important Schiff bases: An updated Review
SK Raju, A Settu, A Thiyagarajan, D Rama… - World Journal of …, 2022 - academia.edu
The Schiff base defined by an imine or azomethine (-CH= N-) group, is mostly synthesized
by the condensation reaction of carbonyl compounds (Aldehyde or Ketone) with compounds …
by the condensation reaction of carbonyl compounds (Aldehyde or Ketone) with compounds …
[HTML][HTML] 1, 2, 3-triazole and chiral Schiff base hybrids as potential anticancer agents: DFT, molecular docking and ADME studies
Abstract A series of novel 1, 2, 3-triazole and chiral Schiff base hybrids 2–6 were
synthesized by Schiff base condensation reaction from pre-prepared parent component of …
synthesized by Schiff base condensation reaction from pre-prepared parent component of …
[HTML][HTML] Design, synthesis, molecular docking study, and α-glucosidase inhibitory evaluation of novel hydrazide–hydrazone derivatives of 3, 4-dihydroxyphenylacetic …
A series of novel Schiff base derivatives (1–28) of 3, 4-dihydroxyphenylacetic acid were
synthesized in a multi-step reaction. All the synthesized Schiff bases were obtained in high …
synthesized in a multi-step reaction. All the synthesized Schiff bases were obtained in high …
Mechanistic efficacy assessment of selected novel methanimine derivatives against vincristine induced Neuropathy: in-vivo, Ex-vivo and In-silico correlates
Vincristine induced peripheral neuropathy (VIPN) is a serious untoward side effect suffered
by cancer patients, which still lacks an adequate therapeutic approach. This study examined …
by cancer patients, which still lacks an adequate therapeutic approach. This study examined …