Environmental cold-induced injury

GJ Jurkovich - Surgical Clinics, 2007 - surgical.theclinics.com
In the United States, there are more than 650 deaths per year from hypothermia. The
Centers for Disease Control and Prevention reports that between 1979 and 2002, a total of …

Hypothermia in bleeding trauma: a friend or a foe?

T Kheirbek, AR Kochanek, HB Alam - Scandinavian journal of trauma …, 2009 - Springer
The induction of hypothermia for cellular protection is well established in several clinical
settings. Its role in trauma patients, however, is controversial. This review discusses the …

Hypothermia and injury

SA Tisherman - Current opinion in critical care, 2004 - journals.lww.com
The dichotomy between laboratory findings that show a benefit of hypothermia and clinical
findings that suggest detrimental effects remains difficult to explain. For now, preventing …

Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs

X Wu, PM Kochanek, K Cochran, A Nozari… - Journal of Trauma …, 2005 - journals.lww.com
Methods: Pigs were prepared under isoflurane anesthesia. After laparotomy, venous blood
(75 mL/kg) was continuously withdrawn over 3 hours (no systemic heparin). At HS 35 …

Coexpression of vesicular glutamate transporter‐3 and γ‐aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column

RL Stornetta, DL Rosin, JR Simmons… - Journal of …, 2005 - Wiley Online Library
Markers of serotonergic, γ‐aminobutyric acid (GABA)‐ergic (glutamic acid decarboxylase,
67 kDa isoform; GAD‐67), and glutamatergic transmission (vesicular glutamate transporter …

Short-term, mild hypothermia can increase the beneficial effect of permissive hypotension on uncontrolled hemorrhagic shock in rats

T Li, X Lin, Y Zhu, L Li, L Liu - The Journal of the American Society of …, 2012 - pubs.asahq.org
Background Our previous and other studies have shown that hypotensive or hypothermic
resuscitation have beneficial effects on uncontrolled hemorrhagic shock. Whether …

Hypothermia reduces microvascular permeability and reactive oxygen species expression after hemorrhagic shock

EW Childs, KF Udobi, FA Hunter - Journal of Trauma and Acute …, 2005 - journals.lww.com
Background: Hypothermia is a frequent manifestation after trauma-induced hemorrhagic
shock. Clinical studies have suggested that hypothermia is an independent risk variable …

Effects of hypothermia and re-warming on the inflammatory response in a murine multiple hit model of trauma

F Hildebrand, M van Griensven, P Giannoudis… - Cytokine, 2005 - Elsevier
INTRODUCTION: Although, hypothermia is a frequent event after trauma, it is unclear
whether its beneficial or detrimental effects are more important. This study aims to quantify …

Hypothermia is associated with improved outcomes in a porcine model of hemorrhagic shock

ME George, KE Mulier, GJ Beilman - Journal of Trauma and Acute …, 2010 - journals.lww.com
Background: Hypothermia after trauma is, in current medical practice, both avoided and
aggressively treated. However, the effects of environmental hypothermia during early …

Microcirculatory effects of rewarming in experimental hemorrhagic shock

JFC Eguillor, G Ferrara, VSK Edul, MG Buscetti… - Microvascular …, 2023 - Elsevier
Background Rewarming is a recommended therapy during the resuscitation of hypothermic
patients with hemorrhagic shock. In experimental models, however, it increases …