Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man

RJ Fenster, LAM Lebois, KJ Ressler… - Nature Reviews …, 2018 - nature.com
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …

The biological effects of childhood trauma

MD De Bellis, A Zisk - Child and Adolescent Psychiatric …, 2014 - childpsych.theclinics.com
The Biological Effects of Childhood Trauma - Child and Adolescent Psychiatric Clinics Skip to
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Decision making under stress: a selective review

K Starcke, M Brand - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Many decisions must be made under stress, and many decision situations elicit stress
responses themselves. Thus, stress and decision making are intricately connected, not only …

From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders

MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

Post-traumatic stress disorder: the neurobiological impact of psychological trauma

JE Sherin, CB Nemeroff - Dialogues in clinical neuroscience, 2011 - Taylor & Francis
The classic fight-or-flight response to perceived threat is a reflexive nervous phenomenon
thai has obvious survival advantages in evolutionary terms. However, the systems that …

Neuroimaging of child abuse: a critical review

H Hart, K Rubia - Frontiers in human neuroscience, 2012 - frontiersin.org
Childhood maltreatment is a stressor that can lead to the development of behavior problems
and affect brain structure and function. This review summarizes the current evidence for the …

The neurocircuitry of fear, stress, and anxiety disorders

LM Shin, I Liberzon - Neuropsychopharmacology, 2010 - nature.com
Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …

Aberrant resting‐state brain activity in posttraumatic stress disorder: A meta‐analysis and systematic review

SBJ Koch, M van Zuiden, L Nawijn… - Depression and …, 2016 - Wiley Online Library
Background About 10% of trauma‐exposed individuals develop PTSD. Although a growing
number of studies have investigated resting‐state abnormalities in PTSD, inconsistent …

The enduring effects of abuse and related adverse experiences in childhood: A convergence of evidence from neurobiology and epidemiology

RF Anda, VJ Felitti, JD Bremner, JD Walker… - European archives of …, 2006 - Springer
Background Childhood maltreatment has been linked to a variety of changes in brain
structure and function and stress–responsive neurobiological systems. Epidemiological …

Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder

MR Milad, RK Pitman, CB Ellis, AL Gold, LM Shin… - Biological …, 2009 - Elsevier
BACKGROUND: A clinical characteristic of posttraumatic stress disorder (PTSD) is
persistently elevated fear responses to stimuli associated with the traumatic event. The …