Radiotheranostics in oncology: current challenges and emerging opportunities

L Bodei, K Herrmann, H Schöder, AM Scott… - Nature Reviews …, 2022 - nature.com
Structural imaging remains an essential component of diagnosis, staging and response
assessment in patients with cancer; however, as clinicians increasingly seek to …

Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-212/203 Radionuclides: Focus Review

KA Morgan, SE Rudd, A Noor, PS Donnelly - Chemical Reviews, 2023 - ACS Publications
Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

[HTML][HTML] Peptide-drug conjugates: a new hope for cancer management

VP Chavda, HK Solanki, M Davidson… - Molecules, 2022 - mdpi.com
Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …

Cancer treatment using peptides: current therapies and future prospects

J Thundimadathil - Journal of amino acids, 2012 - Wiley Online Library
This paper discusses the role of peptides in cancer therapy with special emphasis on
peptide drugs which are already approved and those in clinical trials. The potential of …

Lutetium-177 therapeutic radiopharmaceuticals: linking chemistry, radiochemistry, and practical applications

S Banerjee, MRA Pillai, FF Knapp - Chemical reviews, 2015 - ACS Publications
Interest in the use of radionuclides for treatment of various diseases has a long history and
parallels the isolation of radium by Marie and Pierre Curie in the early part of the 20th …

[HTML][HTML] Tumor-induced osteomalacia

WH Chong, AA Molinolo, CC Chen… - Endocrine-related …, 2011 - erc.bioscientifica.com
Somatostatin receptor imaging (SRI) with [111 In-DTPA 0] octreotide has proven its role in
the diagnosis and staging of gastroenteropancreatic neuroendocrine tumors (GEPNETs) …

The diagnosis and medical management of advanced neuroendocrine tumors

GA Kaltsas, GM Besser, AB Grossman - Endocrine reviews, 2004 - academic.oup.com
Neuroendocrine tumors (NETs) constitute a heterogeneous group of neoplasms that
originate from endocrine glands such as the pituitary, the parathyroids, and the …

[PDF][PDF] Somatostatin receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors

DJ Kwekkeboom, BL Kam, M Van Essen… - Endocrine-related …, 2010 - researchgate.net
Somatostatin receptor imaging (SRI) with [111In-DTPA0] octreotide has proven its role in the
diagnosis and staging of gastroenteropancreatic neuroendocrine tumors (GEPNETs). Newer …

Opportunities in somatostatin research: biological, chemical and therapeutic aspects

G Weckbecker, I Lewis, R Albert, HA Schmid… - Nature reviews Drug …, 2003 - nature.com
Somatostatins—also known as somatotropin-release inhibiting factors (SRIFs)—are a family
of cyclopeptides that have broad inhibitory effects on the secretion of hormones such as …

Individualized dosimetry of kidney and bone marrow in patients undergoing 177Lu-DOTA-octreotate treatment

M Sandström, U Garske-Román… - Journal of Nuclear …, 2013 - Soc Nuclear Med
The organs at risk in radionuclide therapy with 177Lu-octreotate are the bone marrow and
the kidneys. The primary aim of this study was to develop an individualized dosimetry …