Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Cardiovascular disease is the leading cause of death worldwide, with this trend predicted to
continue for the foreseeable future. Common disorders are associated with the stenosis or …

Collagen is regarded as one of the most useful biomaterials. The excellent biocompatibility
and safety due to its biological characteristics, such as biodegradability and weak …

Cardiovascular diseases (CVDs) account for the 31% of total death per year, making them
the first cause of death in the world. Atherosclerosis is at the root of the most life-threatening …

Tissue engineering is an interdisciplinary and multidisciplinary field. It has shown great
promise in generating living alternatives for harvested tissues and organs for transplantation …

Most organs and biological tissues are soft viscoelastic materials with elastic moduli ranging
from on the order of 100 Pa for the brain to 100 000 Pa for soft cartilage. Biocompatible …

Modern synthetic biomaterials are being designed to integrate bioactive ligands within
hydrogel scaffolds for cells to respond and assimilate within the matrix. These advanced …

Fibroblasts differentiate into the highly synthetic and contractile myofibroblast phenotype
when exposed to substrates with an elastic modulus corresponding to pathologically stiff …

Human bioartificial muscles (HBAMs) are tissue engineered by suspending muscle cells in
collagen/MATRIGEL, casting in a silicone mold containing end attachment sites, and …

Collagen type I is a widely used natural biomaterial that has found utility in a variety of
biological and medical applications. Its well-characterized structure and role as an …