Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

Early detection of cancer

D Crosby, S Bhatia, KM Brindle, LM Coussens, C Dive… - Science, 2022 - science.org
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …

Application of nanomaterials in biomedical imaging and cancer therapy

S Siddique, JCL Chow - Nanomaterials, 2020 - mdpi.com
Nanomaterials, such as nanoparticles, nanorods, nanosphere, nanoshells, and nanostars,
are very commonly used in biomedical imaging and cancer therapy. They make excellent …

Metabolic analysis as a driver for discovery, diagnosis, and therapy

RJ DeBerardinis, KR Keshari - Cell, 2022 - cell.com
Metabolic anomalies contribute to tissue dysfunction. Current metabolism research spans
from organelles to populations, and new technologies can accommodate investigation …

Clinical development of metabolic inhibitors for oncology

KM Lemberg, SS Gori, T Tsukamoto… - The Journal of …, 2022 - Am Soc Clin Investig
Metabolic inhibitors have been used in oncology for decades, dating back to antimetabolites
developed in the 1940s. In the past 25 years, there has been increased recognition of …

Hyperpolarized 13C MRI: State of the Art and Future Directions

ZJ Wang, MA Ohliger, PEZ Larson, JW Gordon, RA Bok… - Radiology, 2019 - pubs.rsna.org
Hyperpolarized (HP) carbon 13 (13C) MRI is an emerging molecular imaging method that
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …

In Vivo Metabolic Imaging of [1‐13C]Pyruvate‐d3 Hyperpolarized By Reversible Exchange With Parahydrogen**

H de Maissin, PR Groß, O Mohiuddin… - Angewandte Chemie …, 2023 - Wiley Online Library
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …

MRI-guided radiation therapy: an emerging paradigm in adaptive radiation oncology

R Otazo, P Lambin, JP Pignol, ME Ladd… - Radiology, 2021 - pubs.rsna.org
Radiation therapy (RT) continues to be one of the mainstays of cancer treatment.
Considerable efforts have been recently devoted to integrating MRI into clinical RT planning …

Imaging breast cancer using hyperpolarized carbon-13 MRI

FA Gallagher, R Woitek, MA McLean… - Proceedings of the …, 2020 - National Acad Sciences
Our purpose is to investigate the feasibility of imaging tumor metabolism in breast cancer
patients using 13C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized …

Synthesis, properties, and applications of fluorescent diamond particles

OA Shenderova, AI Shames, NA Nunn… - Journal of Vacuum …, 2019 - pubs.aip.org
Diamond particles containing color centers—fluorescent crystallographic defects embedded
within the diamond lattice—outperform other classes of fluorophores by providing a …