The composition of the gut microbiota is highly dynamic and changes according to various
conditions. The gut microbiota mainly includes difficult-to-cultivate anaerobic bacteria, hence …

Antimicrobial resistance is a major concern. Epidemiological studies have demonstrated
direct relationships between antibiotic consumption and emergence/dissemination of …

Antimicrobial resistance (AMR) is a threat to global public health and the identification of
genetic determinants of AMR is a critical component to epidemiological investigations. High …

Background Enterobacteriaceae have become increasingly resistant, especially due to the
acquisition and spread of extended-spectrum beta-lactamases (ESBLs), which confer …

The ongoing pandemic of extended-spectrum β-lactamase-producing Enterobacteriaceae
(ESBL-E) is responsible for a global rise in carbapenem consumption that may hasten the …

Highlights•The gut microbiota is regarded nowadays as a key component for human
health.•Dysbiosis is an unrecognized disease whose consequences just begin to be …

Introduction Carbapenems are broad-spectrum antibacterial molecules. Imipenem-cilastatin
and meropenem are the two main molecules used in French healthcare services. Objective …

Antibiotic resistance is increasing worldwide and poses a fundamental, long-term threat to
human health. Solutions tackling antibiotic resistance include the protection of our intestinal …

Background: The R-GNOSIS (Resistance in Gram-Negative Organisms: Studying
Intervention Strategies) WP3 study was the first multicenter randomized clinical trial …

Pseudomonas aeruginosa, a Gram-negative bacterium, is a member of the ESKAPE
pathogens and one of the leading causes of healthcare-associated infections worldwide …