Solvent-solute interaction, thermodynamic behaviour, structural, chemical and anti-cancer biological properties of 3 (2H)-furanone derivatives

SC Parakkal, R Datta, S Muthu, NS Alharbi… - Journal of Molecular …, 2023 - Elsevier
In this work, the structures, reactivities, and electronic and biological properties of the 3 (2H)-
furanone derivatives, 2-hydroxy-2, 5-diphenyl-4-(phenylamino) furan-3 (2H)-one (HDPF), 2 …

[HTML][HTML] Green synthesis of bimetallic AgZnO Nanoparticles: Synergistic anticancer effects through regulation of gene expression for lung cancer treatment

NA Moghaddam, A Eskandari, B Khodadadi… - Results in …, 2024 - Elsevier
Lung cancer is the foremost diagnosed cancer in men and the second most common cancer
worldwide, highlighting the need for new treatment strategies. In the current study, AgZnO …

Quantum computational, solvation and in-silico biological studies of a potential anti-cancer thiophene derivative

R Abhijith, SC Parakkal, R Datta, NS Alharbi… - Journal of Molecular …, 2024 - Elsevier
Heterocyclic molecules display a wide spectrum of properties that span both material and
biological domains. Material properties stem from their interactions in the bulk, where a large …

Computational studies into the chemical nature, thermal behaviour, solvent role, reactivity and biological evaluation of Rigidin E–A marine alkaloid with potent liver …

W Hammad, SC Parakkal, R Datta, S Muthu… - Journal of Molecular …, 2023 - Elsevier
The current work includes theoretical studies of Rigidin E (marine alkaloid) molecule with
the DFT technique and evaluation of its biological properties in silico. DFT calculations in …

[HTML][HTML] DFT and molecular docking analyses of the effects of solvent polarity and temperature on the structural, electronic, and thermodynamic properties of p …

U Sherefedin, A Belay, K Gudishe, A Kebede… - Results in Physics, 2024 - Elsevier
This study investigated the effects of solvent polarity and temperature on the structural,
electronic, and thermodynamic properties of p-coumaric acid (p-CA) and its interaction with …

Structural, electronic, intermolecular interaction, reactivity, vibrational spectroscopy, charge transfer, Hirshfeld surface analysis, pharmacological and hydropathy plot …

R Sravanthi, S Mahalakshmi, S Kumaran… - Heliyon, 2023 - cell.com
The therapeutic properties of 5-Bromonicotinatic acid (5BNA) were studied for antiviral
illnesses like Hepatitis A, Hepatitis B and Hepatitis C and the influence of electron-donating …

Computational study of charge transfer iso-surface in first three excited states, electron-hole transition effects, chemical nature and bond order analysis investigations …

JJ Bhargiri, SC Parakkal, R Datta, NS Alharbi… - Computational and …, 2024 - Elsevier
This work presents the theoretical DFT (Density Functional Theory) studies and the
biological application of chrysogine, a marine alkaloid. Energy minimisation and additional …

Quantum computational, charge density, optical, molecular reactivity and thermodynamical analysis of Di-Halogen substituted nicotinic acid derivatives

R Sravanthi, S Mahalakshmi, A Saral… - Computational and …, 2024 - Elsevier
Chloro-3-fluoro-2-(trifluoromethyl) isonicotinic acid (6C3F2TINA) and 6-Chloro-5-
fluoronicotinic acid (6C5FNA) are currently being studied using the DFT method for the …

Computational investigation into the structure, effect of band gap energies, charge transfer, reactivity, thermal energies and NADPH inhibitory activity of a …

R Abhijith, R Datta, S Sakthivel, JM Khaled… - Computational and …, 2024 - Elsevier
This work contains computational investigations of a benzimidazole derivative consisting of
density functional theory, electronic structure and biological evaluation of a benzimidazole …

Characterization of the Cytotoxic Effect of Naphthalenacetamides Hydrochlorides on Cervical Cancer-Derived Cells

C Martínez-Nava, C Pérez-González… - Medicinal …, 2024 - benthamdirect.com
Introduction Cervical cancer is a global health problem due to its high incidence and
prevalence in women, mainly in third-world countries. For the treatment of this disease, there …